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Biweekly cetuximab in combination with FOLFOX-4 in the first-line treatment of wild-type KRASmetastatic colorectal cancer: final results of a phase II, open-label, clinical trial (OPTIMIX-ACROSS Study)

机译：西妥昔单抗与FOLFOX-4联合双周治疗野生型KRAS转移性结直肠癌的一线治疗：II期开放标签临床试验的最终结果（OPTIMIX-ACROSS研究）

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Julen Fernandez-Plana; Carlos Pericay; Guillermo Quintero; Vicente Alonso; Antonieta Salud; Miguel Mendez; Mercedes Salgado; Eugeni Saigi; Luis Cirera;
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1. CMAB009联合伊立替康或伊立替康单药二线治疗氟嘧啶和奥沙利铂治疗失败的KRAS野生型转移性结直肠癌患者的研究:一项前瞻性、开放、随机、Ⅲ期试验 [J] . 石远凯, 白丽, 张沂平, 癌症（英文版） . 2020,第007期
2. Biweekly cetuximab in combination with FOLFOX-4 in the first-line treatment of wild-type KRAS metastatic colorectal cancer: final results of a phase II, open-label, clinical trial (OPTIMIX-ACROSS Study) [J] . Julen Fernandez-Plana, Carlos Pericay, Guillermo Quintero, BMC Cancer . 2014,第1期

机译：双周西妥昔单抗联合FOLFOX-4一线治疗野生型KRAS转移性结直肠癌：II期开放标签临床试验的最终结果（OPTIMIX-ACROSS研究）
3. Efficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial [J] . Qin Shukui, Li Jin, Wang Liwei, Journal of Clinical Oncology . 2018,第30期

机译：一线Cetuximab和Leucovorin，氟尿嘧啶和Oxaliplatin（Folfox-4）对RAS野生型转移性结肠直肠癌患者的疗效和耐受性，与Folfox-4相比：开放标签，随机，第III期裁缝试验
4. Treatment sequence with either irinotecan/cetuximab followed by FOLFOX-4 or the reverse strategy in metastatic colorectal cancer patients progressing after first-line FOLFIRI/bevacizumab: An Italian Group for the Study of Gastrointestinal Cancer phase III, randomised trial comparing two sequences of therapy in colorectal metastatic patients [J] . European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2017,第期

机译：用伊立替康/西替昔单抗的治疗序列，然后进行Folfox-4或转移性结肠直肠癌患者的反向策略，在第一线Folfiri / Bevacizumab后进展：用于研究胃肠癌期III的意大利组，随机试验比较两种治疗序列结肠直肠转移性患者
5. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
6. Clinical predictive value of pre-clinical cancer models: A study of the predictive value of the in vitro cell line, human xenograft and murine allograft pre-clinical cancer models for phase II clinical trials of cytotoxic cancer drugs [D] . Voskoglou-Nomikos, Theodora 2001

机译：临床前癌症模型的临床预测价值：体外细胞系，人异种移植和小鼠同种异体移植临床前癌症模型对细胞毒性癌症药物II期临床试验的预测价值研究
7. Biweekly cetuximab in combination with FOLFOX-4 in the first-line treatment of wild-type KRAS metastatic colorectal cancer: final results of a phase II open-label clinical trial (OPTIMIX-ACROSS Study) [O] . Julen Fernandez-Plana, Carlos Pericay, Guillermo Quintero, 2014

机译：双周西妥昔单抗联合FOLFOX-4一线治疗野生型KRAS转移性结直肠癌：II期开放标签临床试验的最终结果（OPTIMIX-ACROSS研究）
8. Efficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial [O] . Shukui Qin, Jin Li, Liwei Wang, 2018

机译：一线Cetuximab和Leucovorin，氟尿嘧啶和Oxaliplatin（Folfox-4）对RAS野生型转移性结肠直肠癌患者的疗效和耐受性，与Folfox-4相比：开放标签，随机，第III期裁缝试验

Biweekly cetuximab in combination with FOLFOX-4 in the first-line treatment of wild-type KRASmetastatic colorectal cancer: final results of a phase II, open-label, clinical trial (OPTIMIX-ACROSS Study)

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