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Type I error rates of rare single nucleotide variants are inflated in tests of association with non–normally distributed traits using simple linear regression methods

机译：使用简单的线性回归方法，在与非正态分布性状相关的测试中，稀有单核苷酸变体的I型错误率被夸大了

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Tae-Hwi Schwantes-An; Heejong Sung; Jeremy A. Sabourin; Cristina M. Justice; Alexa J. M. Sorant; Alexander F. Wilson;
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1. Type I error rates of rare single nucleotide variants are inflated in tests of association with non–normally distributed traits using simple linear regression methods [J] . Tae-Hwi Schwantes-An, Heejong Sung, Jeremy A. Sabourin, BMC proceedings. . 2016,第Suppla7期

机译：I型罕见单核苷酸变体的误差率在使用简单的线性回归方法的与非正常分布性状的关联的测试中膨胀
2. Inflated type I error rates when using aggregation methods to analyze rare variants in the 1000 Genomes Project exon sequencing data in unrelated individuals: summary results from Group 7 at Genetic Analysis Workshop 17. [J] . Tintle N, Aschard H, Hu I, Genetic epidemiology. . 2011,第Suppla1期

机译：使用聚合方法分析不相关个体的1000个基因组计划外显子测序数据中的稀有变异时，I型错误率升高：遗传分析研讨会17第7组的总结结果。
3. BETASEQ: a powerful novel method to control type-I error inflation in partially sequenced data for rare variant association testing [J] . Yan Song, Li Yun Bioinformatics . 2014,第4期

机译：BETASEQ：一种功能强大的新颖方法，用于控制部分序列数据中的I型错误填充，以进行稀有变异关联测试
4. Tiled regression reduces type I error rates in tests of association of rare single nucleotide variants with non-normally distributed traits, compared with simple linear regression [C] . Sung Heejong, Sorant Alexa J.M., Sabourin Jeremy A., IEEE International Conference on Bioinformatics and Biomedicine . 2015

机译：与简单的线性回归相比，平铺回归降低了罕见单核苷酸变体与非正态分布特征的关联测试中的I型错误率
5. The effects of errors in the specification of genotype of a single nucleotide polymorphism (SNP) on the chi-squared test of association between disease and SNP type. [D] . Kang, Sun Jung. 2003

机译：单核苷酸多态性（SNP）基因型规范中的错误对疾病与SNP类型之间关联性的卡方检验的影响。
6. Type I error rates of rare single nucleotide variants are inflated in tests of association with non–normally distributed traits using simple linear regression methods [O] . Tae-Hwi Schwantes-An, Heejong Sung, Jeremy A. Sabourin, 2016

机译：使用简单的线性回归方法在与非正态分布性状相关的测试中稀有单核苷酸变体的I型错误率被夸大了
7. Inflated type I error rates when using aggregation methods to analyze rare variants in the 1000 Genomes Project exon sequencing data in unrelated individuals: Summary results from Group 7 at Genetic Analysis Workshop 17 [O] . Tintle, N., Aschard, H., Hu, I., 2011

机译：使用聚合方法分析不相关个体的1000个基因组计划外显子测序数据中的稀有变异时，I型错误率上升：遗传分析研讨会17第7组的总结结果

Type I error rates of rare single nucleotide variants are inflated in tests of association with non–normally distributed traits using simple linear regression methods

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