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Combining targeted and immunotherapy: BRAF inhibitor dabrafenib (D) ± the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation-positive unresectable or metastatic melanoma (MM)

机译：结合靶向治疗和免疫治疗：BRAF抑制剂dabrafenib（D）±MEK抑制剂曲美替尼（T）与ipilimumab（Ipi）联合治疗V600E / K突变阳性的不可切除或转移性黑色素瘤（MM）

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1. Combining targeted and immunotherapy: BRAF inhibitor dabrafenib (D) ± the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation-positive unresectable or metastatic melanoma (MM) [J] . Igor Puzanov Journal of Translational Medicine . 2015,第SUPPLEMENTa1期

机译：结合靶向治疗和免疫治疗：BRAF抑制剂dabrafenib（D）±MEK抑制剂曲美替尼（T）与ipilimumab（Ipi）联合治疗V600E / K突变阳性的不可切除或转移性黑色素瘤（MM）
2. Response to Ipilimumab/Nivolumab Rechallenge and BRAF Inhibitor/MEK Inhibitor Rechallenge in a Patient with Advanced Metastatic Melanoma Previously Treated with BRAF Targeted Therapy and Immunotherapy [J] . Caitlyn N. Myrdal, Srinath Sundararajan Case Reports in Oncological Medicine . 2020,第3期

机译：对Ipilimumab / Nivolumab重新检查和BRAF抑制剂/ MEK抑制剂在患者中重新检查，所述患者预先用BRAF靶向治疗和免疫治疗治疗
3. The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4 [J] . Liu Li, Mayes Patrick A., Eastman Stephen, Clinical cancer research: an official journal of the American Association for Cancer Research . 2015,第7期

机译：BRAF和MEK抑制剂Dabrafenib和Trametinib：对免疫功能的影响以及与靶向PD-1，PD-L1和CTLA-4的免疫调节抗体的组合
4. Gene Expression Models of BRAF Inhibitor Resistance in Melanoma Predict Drug Repurposing Candidates for Novel Combination Therapies [C] . Kelly Regan, Andrew R. Stiff, William E. Carson, International Molecular Medicine Tri-Conference. . 2016

机译：黑色素瘤中BRAF抑制剂抗性的基因表达模型预测了新型组合疗法的药物重新培养候选者
5. Optimizing MEK Inhibitors in NRAS Mutant Melanoma - Overcoming Resistance and Combination Strategies [D] . Nguyen, Mai. 2021

机译：优化NRAS突变体黑素瘤耐久性和组合策略中的MEK抑制剂
6. Combining targeted and immunotherapy: BRAF inhibitor dabrafenib (D) ± the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation-positive unresectable or metastatic melanoma (MM) [O] . Igor Puzanov 2015

机译：结合靶向治疗和免疫治疗：BRAF抑制剂dabrafenib（D）±MEK抑制剂曲美替尼（T）与ipilimumab（Ipi）联合治疗V600E / K突变阳性的不可切除或转移性黑色素瘤（MM）
7. The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4 [O] . Li Liu, Patrick A. Mayes, Stephen Eastman, 2015

机译：BRAF和MEK抑制剂Dabrafenib和Trametinib：对免疫功能的影响，以及靶向PD-1，PD-L1和CTLA-4的免疫调节抗体的影响

Combining targeted and immunotherapy: BRAF inhibitor dabrafenib (D) ± the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation-positive unresectable or metastatic melanoma (MM)

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