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Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts

机译：Mek抑制导致针对转移性黑素瘤患者衍生的黑色素球和黑色素球生成的异种移植物的显着抗肿瘤活性

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Giovanni Sette; Katia Fecchi; Valentina Salvati; Fiorenza Lotti; Emanuela Pilozzi; Enrico Duranti; Mauro Biffoni; Alfredo Pagliuca; Daniela Martinetti; Lorenzo Memeo; Michele Milella; Ruggero De Maria; Adriana Eramo;
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1. Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts [J] . Giovanni Sette, Katia Fecchi, Valentina Salvati, Journal of experimental & clinical cancer research : . 2013,第1期

机译：Mek抑制导致针对转移性黑素瘤患者衍生的黑色素球和黑色素球生成的异种移植物的显着抗肿瘤活性
2. Metastatic Melanoma Patient-Derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition [J] . Shattuck-Brandt Rebecca L., Chen Sheau-Chiann, Murray Emily, Clinical cancer research: an official journal of the American Association for Cancer Research . 2020,第14期

机译：转移性黑色素瘤患者衍生的异种移植物响应MDM2抑制作用或与BRAF / MEK抑制组合
3. Antitumor Activity of the MEK Inhibitor TAK-733 against Melanoma Cell Lines and Patient-Derived Tumor Explants [J] . Micel Lindsey N., Tentler John J., Tan Aik-Choon, Molecular cancer therapeutics . 2015,第2期

机译：MEK抑制剂TAK-733对黑素瘤细胞系和患者衍生的肿瘤植株的抗肿瘤活性
4. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [C] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Molecular-Guided Surgery: Molecules, Devices, and Applications IV . 2018

机译：荧光人源化抗CEA抗体在源自患者的原位异种移植（PDOX）小鼠模型中特异性标记转移性胰腺癌
5. Wnt5a Signaling Induced Phosphorylation Increases Acyl Protein Thioesterase 1 Activity and Promotes Melanoma Metastatic Behavior [D] . Sadeghi, Rochelle Shirin. 2018

机译：Wnt5a信号传导诱导的磷酸化增加酰基蛋白硫酯酶1活性并促进黑素瘤转移性行为
6. Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts [O] . Giovanni Sette, Katia Fecchi, Valentina Salvati, 2013

机译：Mek抑制导致针对源自患者的转移性黑色素瘤和黑色素球生成的异种移植物的显着抗肿瘤活性
7. Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts [O] . Giovanni Sette, Katia Fecchi, Valentina Salvati, 2013

机译：Mek抑制导致针对转移性黑素瘤患者衍生的黑色素球和黑色素球生成的异种移植物的显着抗肿瘤活性

Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts

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