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Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-α activation via the mitogen-activated protein kinase pathway

机译：胰岛素样生长因子（IGF）-I消除了妊娠相关的大鼠乳癌致癌保护：证据表明，IGF-I通过促分裂原激活的蛋白激酶途径通过雌激素受体-α激活增强了癌症进展

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Gudmundur Thordarson; Nicole Slusher; Harriet Leong; Dafne Ochoa; Lakshmanaswamy Rajkumar; Raphael Guzman; Satyabrata Nandi; Frank Talamantes;
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1. Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-α activation via the mitogen-activated protein kin [J] . Gudmundur Thordarson, Nicole Slusher, Harriet Leong, Breast Cancer Research . 2004,第4期

机译：胰岛素样生长因子（IGF）-I消除了妊娠相关的大鼠乳腺致癌作用的保护作用：证据表明IGF-I通过促分裂原激活的蛋白激酶通过雌激素受体-α激活增强癌症进展
2. Inhibition of mitogen-activated protein kinase kinase selectively inhibits cell proliferation in human breast cancer cells displaying enhanced insulin-like growth factor I-mediated mitogen-activated protein kinase activation. [J] . Hermanto U, Zong CS, Wang LH Cell Growth & Differentiation: The Molecular Biology Journal of the American Association for Cancer Research . 2000,第12期

机译：抑制有丝分裂原激活的蛋白激酶激酶选择性抑制人乳腺癌细胞的细胞增殖，显示出胰岛素样生长因子I介导的有丝分裂原激活的蛋白激酶激活增强。
3. Substrate-bound insulin-like growth factor (IGF)-I-IGF binding protein-vitronectin-stimulated breast cell migration is enhanced by coactivation of the phosphatidylinositide 3-Kinase/AKT pathway by alphav-integrins and the IGF-I receptor. [J] . Hollier BG, Kricker JA, Van-Lonkhuyzen DR, Endocrinology . 2008,第3期

机译：底物结合的胰岛素样生长因子（IGF）-I-IGF结合蛋白-玻连蛋白刺激的乳腺细胞迁移通过alphav-整合素和IGF-I受体对磷脂酰肌醇3-激酶/ AKT途径的共激活而增强。
4. Role of the insulin-like growth factor 1 (IGFl)/phosphoinositide-3-kinase (PI3K) pathway mediating physiological cardiac hypertrophy [C] . Julie R. McMullen, Seigo Izum Symposium on heart failure: Molecules, mechanisms and therapeutic targets . 2006

机译：介导生理心脏肥大的胰岛素样生长因子1（IGFL）/磷酸膦酸碱基-3-激酶（PI3K）途径的作用
5. Autocrine mechanisms of action of insulin-like growth factor I (IGF-I) and hormonal regulation of expression of IGF-binding proteins in mammary epithelial cells. [D] . Romagnolo, Donato. 1993

机译：胰岛素样生长因子I（IGF-I）的自分泌作用机制和乳腺上皮细胞中IGF结合蛋白表达的激素调节。
6. Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-α activation via the mitogen-activated protein kinase pathway [O] . Gudmundur Thordarson, Nicole Slusher, Harriet Leong, 2004

机译：胰岛素样生长因子（IGF）-I消除了妊娠相关的大鼠乳癌致癌保护：证据表明IGF-I通过促分裂原激活的蛋白激酶途径通过雌激素受体-α激活增强了癌症进展
7. Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-α activation via the mitogen-activated protein kinase pathway [O] . Thordarson Gudmundur, Slusher Nicole, Leong Harriet, 2004

机译：胰岛素样生长因子（IGF）-I消除了妊娠相关的大鼠乳癌致癌保护：证据表明，IGF-I通过促分裂原激活的蛋白激酶途径通过雌激素受体-α激活增强了癌症进展

Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-α activation via the mitogen-activated protein kinase pathway

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