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Changes of immunoregulatory index among young children suffering from rotavirus intestinal infection

机译:轮状病毒肠道感染的幼儿免疫调节指数的变化

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摘要

Rotavirus infection occupies an important place in theudstructure of infectious diseases and is the main reason of morbidityudand mortality in young children. According to WHO experts, almostudevery child suffers from rotavirus gastroenteritis during the first fiveudyears of life, regardless of social and economic status and place ofudresidence. Children under the age from 6 to 24 months suffer fromudrotavirus infection the most often. According to WHO, the incidenceudin different countries ranges from 250 to 3,000 per 100,000 children.udMore than 111 million cases of rotavirus gastroenteritis areuddiagnosed every year. The course of the disease mostly depends onudthe immune system of the patient. A special place here belongs to theudcell role, namely the immunoregulatory index, which is the ratio ofudCD4 + to CD8 + T-lymphocytes and is an indicator of body's defenseudsystem against infections.
机译:轮状病毒感染在传染病的结构中占有重要地位,是幼儿发病率和成年死亡率的主要原因。据世卫组织专家称,几乎每个孩子在其生命的头 5年内都患有轮状病毒胃肠炎,而不论其社会和经济状况以及居住地点如何。 6至24个月以下的儿童最常感染轮状病毒。根据世界卫生组织的数据,不同国家的发病率范围为每10万儿童250至3,000。 ud每年诊断出超过1.11亿例轮状病毒肠胃炎病例。病程主要取决于患者的免疫系统。 udcell的作用在这里是一个特殊的地方,即免疫调节指数,它是udCD4 +与CD8 + T淋巴细胞的比率,是人体防御感染的指标。

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