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Rediscovering Heart Failure: The contemporary burden and profile of heart failure in Australia

机译:重新发现心力衰竭:澳大利亚心力衰竭的当代负担和概况

摘要

We undertook a study of the contemporary burden of heart failure to complement a previous report released more than a decade ago. During that time, a combination of population dynamics (an ageing population), an evolving armoury of therapeutics to treat the traditional drivers of heart failure (coronary artery disease and hypertension) and a changing risk factor profile (with more diabetes and obesity than ever before) had the potential to either reduce or increase the impact and burden of heart failure from a whole society perspective.At the same time, the definition of heart failure has evolved and this has provided an extra dimension to the burden it imposes; even if the therapeutic options for affected individuals with so-called heart failure with preserved ejection fraction or diastolic heart failure is limited.We would emphasise that estimating the “theoretical” burden of heart failure based on systematic screening of representative samples from whole populations as an accurate picture of the “actual” clinical burden of heart failure based on real-word clinical practice is fraught with danger and uncertainty. Some of the figures in this report only make sense if you accept that a problem is only as big as you can quantify it. In so-called Rumsfeld speak we quantify both the “known-known” and the “known-unknown” aspects of heart failure from a population to clinical burden perspective.Noting the above caveats, utilising contemporary Australian data (including the Western Australia Linkage data-set and the landmark Canberra Heart Study), we were able to update our estimates and provide, what we would regard as a valid and relatively accurate picture of the contemporary burden imposed by heart failure in Australia from an individual to whole society perspective. We would emphasise that much of this burden remains hidden. However, this hidden burden can be likened to the submerged iceberg that feeds the incident cases of clinical heart failure in our community.
机译:我们对当代心力衰竭的负担进行了研究,以补充十多年前发布的先前报告。在这段时间里,人口动态(人口老龄化),不断发展的治疗传统心力衰竭(冠状动脉疾病和高血压)的治疗方法以及不断变化的危险因素(糖尿病和肥胖症比以往任何时候都多)的综合症相结合)有可能从整个社会的角度减少或增加心力衰竭的影响和负担。与此同时,心力衰竭的定义已经演变,这为其施加的负担提供了额外的维度;即使对于保留射血分数或舒张性心力衰竭的所谓心力衰竭患者的治疗选择有限。我们将强调,应根据对整个人群中有代表性的样本进行系统筛查来估算心力衰竭的“理论”负担基于真实的临床实践,心力衰竭的“实际”临床负担的准确描述充满了危险和不确定性。本报告中的某些数字只有在您接受到问题仅能量化时才有意义的情况下才有意义。在所谓的拉姆斯菲尔德演讲中,我们从人群到临床负担的角度对心力衰竭的“已知的”和“未知的”方面进行了量化。注意上述警告,利用当代澳大利亚数据(包括西澳大利亚州链接数据) -集和具有里程碑意义的堪培拉心脏研究),我们能够更新我们的估计并提供从个人到整个社会的角度,我们认为这是对澳大利亚心力衰竭造成的当代负担的有效且相对准确的描述。我们要强调的是,许多这种负担仍然是隐藏的。但是,这种隐藏的负担可以比作是淹没在冰山中的冰山,它为我们社区中临床心力衰竭的事件提供了营养。

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