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Annual report Surveillance of influenza and other respiratory infections in the Netherlands: Winter 2016/2017

机译:荷兰的流感和其他呼吸道感染年度监测报告:2016/2017年冬季

摘要

During the 2016/2017 winter season, the influenza epidemic in the Netherlands lasted for 15 weeks. This was longer than the nine-week average duration of epidemics in the twenty previous seasons. Influenza subtype A(H3N2) was the dominant influenza virus throughout the season. In general, baseline natural immunity against A(H3N2) is relatively low among the elderly. Indeed, the number of patients older than 65 years, who visited a general practitioner (GP) for influenza-like symptoms, was higher than last year when influenza A(H1N1)pdm09 predominated. In nursing homes, the number of patients with influenza-like symptoms was also high. In total, an estimated 500,000 patients had symptomatic influenza in the period between the beginning of October 2016 and the end of May 2017 and 6,500 patients were admitted to hospital for influenza-related symptoms. During the epidemic, there were 7,500 more deaths than expected in this 15-week period. The effectiveness of the influenza vaccine against the A(H3N2) virus was 47 per cent. The circulating Dutch A(H3N2) viruses displayed a good to moderate match with the strain that was used in the 2016 vaccine. The WHO has recommended that the same strain be used for the trivalent vaccine for the 2017/2018 season in the northern hemisphere. The B component in the 2017 trivalent vaccine also remains the same as it was in 2016, but the A(H1N1)pdm09 component will be replaced with a more recent virus. The effectiveness of the vaccine varies every season because it is never known which influenza virus(es) will dominate in the next influenza season. Also, the circulating influenza viruses can evolve over time and deviate from the chosen vaccine viruses. There were more reports of the notifiable respiratory infectious diseases made in the 2016 calendar year than in previous years: tuberculosis (889 notifications), psittacosis (60 notifications) and legionellosis (454 notifications). The increase in legionellosis notifications may be associated with the warm, wet weather conditions in 2016. However, several geographic clusters were observed whose existence could not be explained by heavy rainfall or other weather conditions and for none of these clusters could the source of infection be found. The number of notifications for Q fever (14 notifications) is still decreasing. However, the notifiable infectious diseases that present as pneumonia are notoriously underreported because most cases of community-acquired pneumonia are managed in primary care without specific diagnostic laboratory tests being made.
机译:在2016/2017冬季,荷兰的流感流行持续了15周。这比前二十个季节的九周平均流行时间长。在整个季节中,甲型H3N2流感是主要的流感病毒。通常,老年人中针对A(H3N2)的基线自然免疫力相对较低。实际上,因甲型流感(H1N1)pdm09占主导地位而去过全科医生(GP)以出现类似流感的症状的65岁以上的患者人数要高于去年。在疗养院中,具有流感样症状的患者数量也很高。在2016年10月开始至2017年5月底期间,估计总共有500,000名有症状流感患者,并且有6,500名因流感相关症状入院的患者。在这一流行病期间,这15周内死亡人数比预期多7500人。针对A(H3N2)病毒的流感疫苗的有效性为47%。循环中的荷兰A(H3N2)病毒与2016年疫苗中使用的菌株表现出良好至中等的匹配度。世界卫生组织建议在北半球将相同的菌株用于2017/2018季节的三价疫苗。 2017年三价疫苗中的B成分也与2016年相同,但A(H1N1)pdm09成分将被更新的病毒取代。疫苗的有效性在每个季节都有所不同,因为尚不知道在下一个流感季节将主导哪种流感病毒。而且,循环中的流感病毒会随着时间的流逝而发展,并偏离所选的疫苗病毒。 2016日历年报告的法定呼吸道传染病报告比往年更多:结核病(889例),鹦鹉热(60例)和军团菌病(454例)。军团菌病通报的增加可能与2016年温暖潮湿的天气状况有关。但是,观察到几个地理簇,其存在无法用强降雨或其他天气条件来解释,而且这些簇中没有一个是传染源找到了。 Q发热的通知数量(14个通知)仍在减少。但是,众所周知,肺炎应报告的传染病报告不足,因为大多数社区获得性肺炎病例都是在初级保健中进行管理的,而没有进行专门的诊断实验室检查。

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