The occurrence of Carcinogenic, Mutagenic andReprotoxic (CMR) substances in consumer preparations

摘要

The general public is protected from the effects of Carcinogenic,Mutagenic and Reprotoxic (CMR) substances partly by banning the sale ofpreparations containing classified CMR substances (Annex I of 67/548/EEC)at levels above the limit concentration for exposure of the generalpublic. It is therefore important that consumer preparations are checkedfor the presence of these substances and that, in addition, potential CMRsubstances are assessed for inclusion in Annex I of 67/548/EEC. A searchwas made for potential CMR substances in electronically accessibledatabases, after which a list of 514 potential CMR substances not foundin Annex 1 could be compiled. The occurrence of CMR category 1 and 2substances, and of additional potential CMR substances, in consumerpreparations was checked against the SPIN database, an initiative of theNordic countries. A total of 146 Annex I substances for the CMRcategories 1 and 2, and 24 potential CMR substances were found to bepresent in consumer preparations used in the Nordic countries. It cannotbe ruled out that these substances will also be present in consumerpreparations used in the Netherlands. A quantitative estimate of thepotential exposure to CMR substances was not possible due to the lack ofan adequate database of consumer preparations showing actualconcentrations.