Tomographie hybride simultanée TEP/TDM combinant détecteurs à pixels hybrides et modules phoswich à scintillateurs

摘要

The combination of Positron Emission Tomography (PET) and X-ray Computerized Tomographie (CT) for PET/CT imaging has been an essential line of research in the previous decades and led to a rapid expansion of this technique in clinics and preclinics. However, even if the two modalities can be juxtaposed on the same gantry, the original concept invented by David W. Townsend foresaw to do both PET and CT imaging at the same time, while imaging a common Field-Of-View (FOV). This will allow to know the exactposition of the animal during the scan and possibly to correct for the animal movements. Therefore we developed the ClearPET/XPAD prototype: the first simultaneous PET/CT scanner for mice combining on the same gantry ClearPET modules and the hybrid pixels camera XPAD3 facing an X-ray source. I present the first simultaneous PET/CT scans of point sources, of the Derenzo phantom and of a living mouse acquired with the ClearePET/XPAD prototype and discuss the limitations and prospects of simultaneoushybrid PET/CT imaging.