Habilitation à Diriger des Recherches (HDR) Characterising disordered proteins using nuclear magnetic resonance spectroscopy: Recent developments and future perspectives Caractérisation des protéines désordonnées par résonance magnétique nucléaire: Développements récents et perspectives futures

摘要

This research habilitation focuses on the use of Nuclear Magnetic Resonance (NMR) spectroscopy for studying intrinsically disordered proteins and their interactions at atomic resolution. In particular, special emphasis is put on the development of ensemble descriptions of the proteins on the basis of experimental NMR data and the perspective of combining several NMR parameters with diverse averaging properties into a unified representation of the disordered state.