Objectives: This study aims to compare the sensitivity and specificity of median sensory nerve/ulnar motor nerve latency differenceud(MSUMLD) as a new method with combined sensory index (CSI) for accurate diagnosis of carpal tunnel syndrome.udPatients and methods: The study, which was conducted between November 2013 and May 2014, included 49 patients (7 males, 42 females;udmedian age 45.9±6.6 years; min. 19 - max. 65) and their 97 hands. Of the hands, 47 had symptoms and signs of carpal tunnel syndrome withudnormal routine nerve conduction studies (group 1) and 50 had carpal tunnel syndrome by standard criteria (group 2). Then, MSUMLD andudCSI were performed for the two groups.udResults: The median sensory-ulnar motor latency difference had sensitivity of 86% and specificity of 70%; however, CSI had a sensitivity andudspecificity 72% and 92%, respectively. The median sensory/ulnar motor latency difference was over the normal range in 14/47 hands (29%)udwith normal conventional nerve conduction study. Twenty-nine percent of these patients would be categorized as normal with standard nerveudconduction studies.udConclusion: This new method (MSUMLD) does not need to stimulate more sites during conventional electrodiagnosis and is just a simpleudmathematical practice that may be a complementary method in diagnosis of mild carpal tunnel syndrome.
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