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Effects of Systemic to Pulmonary Shunt on the pulmonary Artery Indices in Children with Pulmonary Atresia and Ventricular Septal Defect

机译:系统性肺分流对肺动脉闭锁和室间隔缺损儿童肺动脉指标的影响

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摘要

Systemic to pulmonary artery shunt is one of the important treatments in pulmonary atresia–ventricular septal defect (PA-VSD). There are controversial views about the effects of shunt on the growth of pulmonary artery tree. The aim of this study was to assess the early and late effects of systemic to pulmonary shunt by angiography on the increase of pulmonary artery indices (Nakata and Mc Goon), and development of complications in patients with PA-VSD. We retrospectively reviewed the results of 19 PA-VSD patients having systemic to pulmonary shunt and had pre and post operation angiography (inclusion criteria). None of them had large collateral or PDA (exclusion criteria). The mean age of the patients was 5 ± 3.6 years. Ten patients had left shunts, 8 cases had right shunts and one case had a central shunt. After shunt the mean increase in Nakata index was 40.8 mm2/m2 (P=0.08) and in McGoon index was 0.11 (P=0.23). A major stenosis was observed in 1 case. The increase of McGoon index was higher in right shunts and in early years after the operation. We can conclude that systemic to pulmonary shunt can be performed with low risk, providing good palliation and is associated with relative increase of pulmonary artery indices (not significant), and low incidence of major stenosis, especially when the shunt was performed in more than two years old patients.
机译:全身至肺动脉分流是肺动脉闭锁-室间隔缺损(PA-VSD)的重要治疗方法之一。关于分流对肺动脉树生长的影响存在争议的观点。这项研究的目的是通过血管造影术评估全身性肺分流对肺动脉指数(Nakata和Mc Goon)增加以及PA-VSD患者并发症发展的早期和晚期影响。我们回顾性回顾了19例PA-VSD患者的全身至肺分流,并在术前和术后进行了血管造影(纳入标准)。他们都没有较大的抵押品或PDA(排除标准)。患者的平均年龄为5±3.6岁。左分流10例,右分流8例,中央分流1例。分流后,中田指数的平均增加为40.8 mm2 / m2(P = 0.08),麦古恩指数的平均增加为0.11(P = 0.23)。 1例出现严重狭窄。右分流术和术后早期,McGoon指数的升高较高。我们可以得出结论,系统性至肺分流的风险低,可提供良好的缓解,并与肺动脉指数的相对增加(不显着)相关,并且严重狭窄的发生率较低,尤其是在两个以上分流的情况下岁的病人。

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