Chemical composition, antibacterial and antifungal activity ofudthree ecotypes of Thymus fallax Fisch. volatile oils

摘要

Background and Aims: Thymus fallax Fisch. is an aromatic plant belonging to the Lamiaceae family,udused for medicinal and spice purposes almost everywhere in the world. In this investigation volatileudoils from three ecotypes of T. fallax have isolated using a Clevenger-type apparatus.udMethods: The quantitative and qualitative analysis was performed by gas chromatography/Massudspectroscopy (GC and GC/Mass). Antibacterial activity of compounds was assayed using the discuddiffusion method against G- and G+ bacteria and some fungi pathogenesis.udResults: Final results shows that Thymol & carvacrol constitute of the main elements present in theudessential oil of T. fallax. In Lamiaceae plants, thymol is always accompanied by its isomer carvacrol.udBoth compounds are biologically active and have potent antibacterial (gram+ and gram-) and antiudfungal activity. The essential oil exhibited strong antioxidant activity.udConclusions: Recognized compounds of Thymus fallax Fisch. volatile oils are biologically active andudhave potent antibacterial (gram+ and gram-) and anti fungal activity. This study also affirmed threeudecotypes volatiale oil had significant effects against G- and G+ bacteria and some fungi pathogenesis.