Ibactericidal and bacteriostatic in vitro effects of teucrium chamaedrys hydroalcoholic extract on two bacterial causative agents of tooth decay

摘要

Tooth decay is a prevalent dental disease and Streptococcus mutans and Lactobacillus rhamnosis are the most important bacterial causes of tooth decay. Because of the increased antibiotic resistance of bacteria and the side effects of antibiotics, this study was conducted to investigate the antibacterial effect of hydroalcoholic Teucrium Chamaedrys extraction S.mutans and L.rhamnosis. In this experimental-laboratory study, T.chamaedrys was extracted by maceration, and the standard strains of lyophilized S.mutans and L.rhamnosis were provided from Iranian Research Organization for Science and Technology for investigation of T.chamaedrys effect on their growth. The antibacterial effect of hydroalcoholic T.chamaedrys was investigated on S.mutans and L.rhamnosis and then minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. The MIC of T. chamaedrys was obtained 128 and 32 μg/L against S.mutans and L.rhamnosis, respectively. The MBC of T.chamaedrys was obtained 256 and 64 μg/L against S.mutans and L.rhamnosis, respectively. T.chamaedrys bactericidal and bacteriostatic effects on L.rhamnosis and S.mutans, two bacterial causative agents of dental cavity show that it might be used for prevention of dental cavity due to these patogens.