sp(3)-sp(2) C-C Bond Formation via Bronsted Acid Trifluoromethanesulfonic Acid-Catalyzed Direct Coupling Reaction of Alcohols and Alkenes

摘要

A novel and efficient trifluoromethanesulfonic acid-catalyzed sp(3)-sp(2) C-C bond formation reaction through the direct coupling of alcohols with alkenes has been realized under mild conditions. The present protocol provides an attractive approach to a diverse range of polysubstituted olefins in good to excellent yields with high stereo- and regioselectivities.