INDIUM-PROMOTED ALLYLATION OF ALKYNES WITH ALLYLIC ALCOHOLS: HIGHLY REGIOSELECTIVE SYNTHESIS OF HALOGEN-SUBSTITUTED 1,4-DIENES

摘要

Indium-promoted allylation of alkynes by direct use of allyl alcohols as the allylating agents has been developed under mild conditions, in which a wide range of allylic alcohols and alkynes (both aromatic and aliphatic alkynes) could be tolerated, and the corresponding halogen-substituted 1,4-dienes were obtained in moderate to excellent yields.