A Novel and Highly Stereoselective Synthesis of 2-Substituted Perhydrofuro2,3-bpyran Derivatives

摘要

An effective and facile method for the synthesis of 2-substituted perhydrofuro[2,3-b]pyran derivatives Is described. The cyclization of 2-C-aldehydo-2-deoxy-D-thioglucoside in the presence of N-iodosuccinimide (NIS) is highly stereoselective. 2-Substituted cyclization products were obtained In good to excellent yields.