Fasting plasma glucose as a screening test for gestational diabetes mellitus : a hospital-based, cross sectional study of 370 antenatal patients in Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia, 1999-2000

摘要

Objektif:udMengkaji glukos plasma berpuasa (fasting plasma glucose) sebagai ujianudpenyaringan bagi penyakit kencing manis ketika mengandung (gestational diabetesudmellitus). Objektif selanjutnya adalah untuk menentukan taburan demografi bagiudpenyakit kencing manis ketika mengandung dan menilai pecahan penyakit ini yanguddapat dikesan melalui saringan selektif menggunakan faktor sejarakudMetodologi:udKajian bersilang telah dijalankan di Hospital Universiti Sains Malaysia (HUSM),udKubang Kerian, Kelantan dari bulan Julai 1999 hingga bulan Oktober 2000. Dataudasas diambil daripada 461 pesakit yang bersetuju mengambil bahagian di dalamudkajian ini, yang mana umur kandungannya tidak melebihi 28 minggu dan tidakudmempunyai penyakit kencing manis sebelum ini. Ujian glukos piawai 2-jam 75-g telahuddijalankan ke atas 370 pesakit. Penyakit kencing manis semasa mengandung danudsubkategorinya iaitu kencing manis dan gangguan toleransi terhadap glukos semasaudmengandung telah didefinasikan oleh mengikut 'Definition, Diagnosis andudClassification of Diabetes Mellitus and its Complications. Part 1 :Diagnosis andudClassification of Diabetes Mellitus Provisional Report of a WHO Consultation'. Ciriciriudsaringan glukos plasma berpuasa dikaji melalui kiraan sensitiviti dan spesifisitiuddengan 'receiver operator characteristic curves'.ududObjective:udTo evaluate fasting plasma glucose as a screening test for gestational diabetes mellitus.udFurther objectives were to determine demographic distribution of gestational diabetesudmellitus and to assess the proportions of gestational diabetes mellitus picked up byudselective screening using historical risk factors alone.udMethods:udA hospital-based, cross-sectional study was carried out at University Hospital,udUniversiti Sains Malaysia (HUSM), Kubang Kerian, Kelantan, from July 1999 tilludOctober 2000. Baseline data from 461 women who agreed to participate in the studyudwith gestational ages less than 28 weeks and no previous diagnosis of diabetes wereudcollected. A standardized 2-h 75-g oral glucose tolerance test was performed in 370udwomen. Gestational diabetes and its subcategories-diabetes and gestational impairedudglucose tolerance-were defined according to the Definition, Diagnosis andudClassification ofDiabetes Mellitus and its Complications. Part !:Diagnosis andudClassification of Diabetes Mellitus Provisional Report of a WHO Consultation.udScreening properties of fasting plasma glucose were evaluated by calculatingudsensitivity and specificity with receiver operator characteristic curves.ud