CCK-A, B受容体及びCCK遺伝子の遺伝的多型 : 精神分裂病との相関研究

摘要

Neuropeptide cholecystokinin(CCK) and its receptors(CCK-AR,CCK-BR) affect the dopaminergic function, which may in turn constitutue a predisposition in schizophrenia. The present study have investigated genetic variations in the promoter region and the coding region of the CCK-AR, CCK-BR and CCK genes. An association analysis was conducted between 83 unrelated schizophrenic patients and 100 healthy controls. ...