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Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation

机译:具有连续光源偏振调制的偏振敏感扫频光学相干层析成像

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摘要

We present fiber-based polarization-sensitive swept-source optical coherence tomography (SS-OCT) based on continuous source polarization modulation. The light source is a frequency swept laser centered at 1.31 μm with a scanning rate of 20 kHz. The incident polarization is modulated by a resonant electro-optic modulator at 33.3 MHz, which is one-third of the data acquisition frequency. The zeroth- and first-order harmonic components of the OCT signals with respect to the polarization modulation frequency have the polarimetric information of the sample. By algebraic and matrix calculations of the signals, this system can measure the depth-resolved Jones matrices of the sample with a single wavelength scan. The phase fluctuations of the starting trigger of wavelength scan and the polarization modulation are cancelled by monitoring the OCT phase of a calibration mirror inserted into the sample arm. We demonstrate the potential of the system by the measurement of chicken breast muscle and the volumetric measurement of an in vivo human anterior eye segment. The phase retardation image shows an additional contrast in the fibrous tissue such as the collagen fiber in the trabecular meshwork and sclera.
机译:我们介绍基于连续源偏振调制的基于光纤的偏振敏感扫描源光学相干断层扫描(SS-OCT)。光源是扫频激光器,其中心频率为1.31μm,扫描速率为20 kHz。入射偏振由谐振电光调制器以33.3 MHz的频率进行调制,这是数据采集频率的三分之一。 OCT信号相对于偏振调制频率的零阶和一阶谐波分量具有样本的偏振信息。通过信号的代数和矩阵计算,该系统可以通过单波长扫描测量样品的深度分辨琼斯矩阵。通过监视插入样品臂的校准镜的OCT相位,可以消除波长扫描和偏振调制的起始触发信号的相位波动。我们通过测量鸡胸肌和体内人眼前段的体积来证明该系统的潜力。相位延迟图像显示了小梁网和巩膜等纤维组织(如胶原纤维)中的附加对比度。

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