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Multistep Lattice-Voxel method utilizing lattice function for Monte-Carlo treatment planning with pixel based voxel model

机译:利用基于像素体素模型的蒙特卡洛治疗计划的利用格函数的多步格子体素方法

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摘要

Treatment planning for boron neutron capture therapy generally utilizes Monte-Carlo methods for calculation of the dose distribution. The new treatment planning system JCDS-FX employs the multi-purpose Monte-Carlo code PHITS to calculate the dose distribution. JCDS-FX allows to build a precise voxel model consisting of pixel based voxel cells in the scale of 0.4×0.4×2.0 mm3 voxel in order to perform high-accuracy dose estimation, e.g. for the purpose of calculating the dose distribution in a human body. However, the miniaturization of the voxel size increases calculation time considerably. The aim of this study is to investigate sophisticated modeling methods which can perform Monte-Carlo calculations for human geometry efficiently. Thus, we devised a new voxel modeling method “Multistep Lattice-Voxel method,” which can configure a voxel model that combines different voxel sizes by utilizing the lattice function over and over. To verify the performance of the calculation with the modeling method, several calculations for human geometry were carried out. The results demonstrated that the Multistep Lattice-Voxel method enabled the precise voxel model to reduce calculation time substantially while keeping the high-accuracy of dose estimation.
机译:硼中子捕获疗法的治疗计划通常利用蒙特卡洛方法来计算剂量分布。新的治疗计划系统JCDS-FX使用多功能的蒙特卡洛代码PHITS来计算剂量分布。 JCDS-FX允许建立一个精确的体素模型,该模型由比例为0.4×0.4×2.0 mm3体素的基于像素的体素单元组成,以执行高精度剂量估算,例如为了计算人体中的剂量分布。但是,体素尺寸的小型化大大增加了计算时间。这项研究的目的是研究可以有效地对人体几何进行蒙特卡洛计算的复杂建模方法。因此,我们设计了一种新的体素建模方法“ Multistep Lattice-Voxel method”,该方法可以通过反复使用晶格函数来配置结合了不同体素大小的体素模型。为了验证使用建模方法进行计算的性能,对人体几何进行了几次计算。结果表明,Multistep Lattice-Voxel方法使精确的体素模型能够显着减少计算时间,同时保持剂量估算的高精度。

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