Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments

摘要

(SS-OCT) system, which uses a ready-to-ship scanning lightsource, is demonstrated. The light source has a center wavelength of 1.31μm, -3 dB wavelength range of 110 nm, scanning rate of 20 KHz, and highlinearity in frequency scanning. This paper presents a simple calibrationmethod using a fringe analysis technique for spectral rescaling. ThisSS-OCT system is capable of realtime display of two-dimensional OCT andcan obtain three-dimensional OCT with a measurement time of 2 s. In vivohuman anterior eye segments are investigated two- and three-dimensionally.The system sensitivity is experimentally determined to be 112 dB. Thethree-dimensional OCT volumes reveal the structures of the anterior eyesegments, which are difficult to observe in two-dimensional OCT images. Atwo dimensional tomographic movie shows a dynamic motion of a humaniris.