Chromium content in different kinds of spanish infant formuale and estimation of dietary intake by infants fed on reconstituted powder formulae

摘要

The essentiality of chromium in humans is well documented. Trivalent chromium, mainchemistry form found in foods, is essential for maintaining normal glucose metabolism.Because of analytical difficulties, several literature reports of chromium content of foods,especially for the lower levels, show large variability and they should be interpreted withcaution for a valid interpretation of reliable results. A Zeeman background correctiontransversely-heated graphite furnace atomic absorption spectrometry was used todetermine the chromium content of 104 different infant formulae (cow’s milk and soyprotein based) marked in Spain following an acid attack sample preparation procedure in aclosed, pressurized and microwave digestion unit.Mean and range chromium values, regarding types and main protein-based infant formulaeare presented. Additionally, the influence of the type of container used, the impact ofindustrial process from different manufacturers and the physical state (powder and liquidformulae) on chromium levels is also discussed. In general, the infant formulae contain ahigher chromium concentration than that found in human milk (reference range: 0.20 –8.18 g l-1), particularly in case of hypoallergenic (18.16 ± 7.89 g l-1), lactose-free (11.37± 3.07 g l-1), preterm (11.48 ± 3.15 g l-1) and soya (10.43 ± 4.05 g l-1) formulae. Themaximum theoretical estimated intake of infant fed on studied formulae was lower than theupper limit safety for trivalent chromium of 1 mg kg-1 (14 g Kg-1 b.w. day-1)recommended by the experts of Council for Responsible Nutrition (CRN ULS, 2004),amounting to about 10 %, 15-18 % and 26 % for standard (adapted and follow-up) andtoddler; soya, lactose-free and preterm; and hypoallergenic formulae, respectively.Therefore, manufacturers are called for continued effort to routinely monitor chromiumlevels, mainly for specialised and preterm formulae, and at the same time, might considerthe inclusion of labelling value for chromium at least in these complex formulations.