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Regulation of HIF1 under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual-Targeting in Patient-Derived 3D Pancreatic Cancer Models

机译：在缺氧下由APE1 / Ref-1调节HIF1影响CA9表达：在患者衍生的3D胰腺癌模型中双重靶向

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Logsdon Derek P.; Grimard Michelle; Shahda Safi; Zyromski Nicholas; Schipani Ernestina; Carta Fabrizio; Supuran Claudiu T.; Korc Murray; Ivan Mircea; Kelley Mark R.; Fishel Melissa L.;
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1. Regulation of HIF1 alpha under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models [J] . Logsdon Derek P., Grimard Michelle, Luo Meihua, Molecular cancer therapeutics . 2016,第11期

机译：在缺氧条件下通过APE1 / Ref-1对HIF1 alpha的调节影响CA9表达：在患者衍生的3D胰腺癌模型中双重靶向
2. Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival [J] . Derek P. Logsdon, Fenil Shah, Fabrizio Carta, Scientific reports. . 2018,第1期

机译：通过CA9和APE1 / REF-1的新抑制剂阻断HIF信号传导显着影响胰腺癌细胞存活率
3. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE1/Ref-1) in human ovarian cancer and indentification of the therapeutic potential of APE1/Ref-1 inhibitor [J] . Ying Zhang, Jian Wang, Debing Xiang, International journal of oncology . 2009,第5期

机译：人卵巢癌中嘌呤/嘧啶内切核酸酶-1 /氧化还原因子-1（APE1 / Ref-1）的表达变化及APE1 / Ref-1抑制剂的治疗潜力
4. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [C] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Molecular-Guided Surgery: Molecules, Devices, and Applications IV . 2018

机译：荧光人源化抗CEA抗体在源自患者的原位异种移植（PDOX）小鼠模型中特异性标记转移性胰腺癌
5. APE1/Ref-1 Redox Signaling Regulates HIF1a-Mediated CA9 Expression in Hypoxic Pancreatic Cancer Cells: Combination Treatment in Patient-Derived Pancreatic Tumor Models [D] . Logsdon, Derek Paul. 2018

机译：APE1 / Ref-1氧化还原信号调节低氧胰腺癌细胞中HIF1a介导的CA9表达：患者源性胰腺肿瘤模型的联合治疗
6. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual-Targeting in Patient-Derived 3D Pancreatic Cancer Models [O] . Derek P. Logsdon, Michelle Grimard, Meihua Luo, -1

机译：低氧对HIF1α的调节通过APE1 / Ref-1影响CA9表达：在患者衍生的3D胰腺癌模型中双重靶向
7. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models [O] . Logsdon, Derek P., Grimard, Michelle, Luo, Meihua, 2016

机译：低氧对HIF1α的调节通过APE1 / Ref-1影响CA9表达：在患者衍生的3D胰腺癌模型中双重靶向

Regulation of HIF1 under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual-Targeting in Patient-Derived 3D Pancreatic Cancer Models

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