Relapsing fever borreliosis is often shrouded in mystery. From its discovery, it has evaded fulfilment of Koch’s postulates. It has resultedudin epidemic waves of infection, although it is now mostly localized to particular endemic pockets of infection. Structurally, this spirochaeteudbreaks many paradigms for conventional microorganisms, e.g. through its segmented genomic structure. Disclosure of host–udmicrobial interactions is revealing a plethora of mechanisms, from antigenic variation to binding of various host-derived proteins. Weuddispel some of the myths and explore current understanding of this much neglected area through a series of reviews within this themeudsection.
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机译:复发性发热性贝氏体病通常笼罩在谜团中。从发现开始,它就没有履行科赫的规定。尽管它现在大多局限于特定的地方性传染病口袋,但它已导致 udin流行病的流行。在结构上,这种螺旋藻突破了许多传统微生物的范式,例如通过其分段的基因组结构。宿主与细菌相互作用的揭示揭示了多种机制,从抗原变异到各种宿主衍生蛋白的结合。我们 u n消除了一些误解,并通过对该主题 u u下的一系列评论来探索对这一被忽视领域的当前理解。
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