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Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs)

机译：细胞周期调节分子pRb，p53和MDM2的表达改变对非小细胞肺癌（NSCLC）的肿瘤生长和染色体不稳定产生协同作用

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Gorgoulis, V.G.; Zacharatos, P.; Kotsinas, A.; Mariatos, G.; Liloglou, T.; Vogiatzi, T.; Foukas, P.; Rassidakis, G.; Garinis, G.; Ioannides, T.; Zoumpourlis, Vassilis; Bramis, J.; Michail, P.O.; Asimacopoulos, P.J.; Field, J.K.; Kittas, Ch.;
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1. hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression [J] . Michael G. Edwards, Katherine Vandervest, John Arcaroli, Biology Open . 2013,第7期

机译：hsa-miR29b（非经典Wnt信号的关键下游靶标）通过靶向MDM2表达在非小细胞肺癌细胞中发挥抗增殖作用hsa-miR29b（非经典Wnt信号的关键下游靶标）通过靶向MDM2表达在非小细胞肺癌细胞中的抗增殖作用hsa-miR29b（非经典Wnt信号的关键下游靶点）通过靶向MDM2表达在非小细胞肺癌细胞中发挥抗增殖作用
2. Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: Relationship with p53 and MDM2 protein expression [J] . Vassilis G Gorgoulis Panayotis Zacharatos Athanassios Kotsinas Triantofillos Liloglou et al The American Journal of Pathology . 1998,第6期

机译：非小细胞肺癌中p16-pRb途径和染色体基因座9p21-22的改变：与p53和MDM2蛋白表达的关系
3. Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs). [J] . Garinis GA, Gorgoulis VG, Mariatos G, Journal of Pathology: Journal of the Pathological Society of Great Britain and Ireland . 2001,第1期

机译：非小细胞肺癌（NSCLC）中FHIT位点的等位基因缺失和p53改变与肿瘤动力学和染色体不稳定性的关系。
4. Inhibition of Non-Small Cell Lung Carcinoma (NSCLC) Tumor Growth by Arginine-Albumin Microspheres [C] . Hung-Yen Lee MS, Kamal A. Mohammed, Zita Burkhalter, Annual meeting of the Society for Biomaterials . 2011

机译：精氨酸-白蛋白微球体抑制非小细胞肺癌（NSCLC）肿瘤的生长
5. Gene expression analysis of human non -small cell lung cancer subtypes, adenocarcinoma and squamous cell carcinoma, and mouse lung epithelial cell lines: Implications in lung tumorigenesis [D] . Silvers, Amy Lynn. 2002

机译：人类非小细胞肺癌亚型，腺癌和鳞状细胞癌以及小鼠肺上皮细胞系的基因表达分析：在肺肿瘤发生中的意义
6. Altered expression of the cell cycle regulatory molecules pRb p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs). [O] . V. G. Gorgoulis, P. Zacharatos, A. Kotsinas, 2000

机译：细胞周期调节分子pRbp53和MDM2的表达改变对非小细胞肺癌（NSCLC）的肿瘤生长和染色体不稳定具有协同作用。
7. Synergistic Tumor Suppression by Coexpression of FHIT and p53 Coincides with FHIT-Mediated MDM2 Inactivation and p53 Stabilization in Human Non-Small Cell Lung Cancer Cells [O] . Masahiko Nishizaki, Ji-ichiro Sasaki, Bingliang Fang, 2004

机译：通过FHIT和P53的共表达和P53的协同肿瘤抑制与人非小细胞肺癌细胞的FHIT介导的MDM2失活和P53稳定化
8. Detection of Human Lung Epithelia Cell Growth Factors Produced by a Lung Carcinoma Cell Line: Use in Culture of Primary Solid Lung Tumors [R] . Siegfried, J. M. 1987

机译：肺癌细胞系产生人肺上皮细胞生长因子的检测：用于原发性肺癌的培养

Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs)

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