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Oxaliplatin plus high-dose folinic acid and 5-fluorouracil i.v. bolus (OXAFAFU) versus irinotecan plus high-dose folinic acid and 5-fluorouracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: a Southern Italy Cooperative Oncology Group phase III trial

机译：奥沙利铂加大剂量亚叶酸和5-氟尿嘧啶静脉注射静脉推注（OXAFAFU）与伊立替康加大剂量亚叶酸和5-氟尿嘧啶静脉内注射转移性结直肠癌患者的大剂量推注（IRIFAFU）：意大利南部合作肿瘤小组III期试验

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摘要

The primary end point of this phase III trial was to compare the response rate (RR) of oxaliplatin (OXA) plus levo-folinic acid (l-FA) and 5-fluorouracil (5-FU) bolus with that of irinotecan (IRI) plus l-FA and 5-FU bolus in advanced colorectal carcinoma.

机译：该III期试验的主要终点是比较奥沙利铂（OXA）加上左亚叶酸（1-FA）和5-氟尿嘧啶（5-FU）推注与依立替康（IRI）的响应率（RR）联合l-FA和5-FU推注治疗晚期大肠癌。

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作者
Comella P; Massidda B; Filippelli G; Palmeri S; Natale D; Farris A; De Vita F; Buzzi F; Tafuto S; Maiorino L; Mancarella S; Leo S; Lorusso V; De Lucia L; Roselli M;
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年度 2005
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1. Oxaliplatin plus high-dose folinic acid and 5-fluorouracil i.v. bolus (OXAFAFU) versus irinotecan plus high-dose folinic acid and 5-fluorouracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: a Southern Italy Cooperative Oncol [J] . Comella P, Massidda B, Filippelli G, Annals of oncology: official journal of the European Society for Medical Oncology . 2005,第6期

机译：奥沙利铂加大剂量亚叶酸和5-氟尿嘧啶静脉注射静脉推注（OXAFAFU）对比伊立替康加大剂量亚叶酸和5-氟尿嘧啶转移性结直肠癌患者的大剂量推注（IRIFAFU）：意大利南部合作社Oncol
2. 3044 POSTER Capecitabine or Folinic acid/Fluorouracil i.v. bolus plus Eloxatin evaluation (COFFE trial) in metastatic colorectal carcinoma (MCRC): final results of the Southern Italy Cooperative Oncology Group (SICOG) phase III trial 0401 [J] . P.Comella, B.Massidda, G.Filippelli, European Journal of Cancer Supplements . 2007,第4期

机译：3044 POSTER卡培他滨或亚叶酸/氟尿嘧啶i.v.转移性结直肠癌（MCRC）推注加依洛沙汀评估（COFFE试验）：意大利南部合作肿瘤小组（SICOG）III期试验0401的最终结果
3. Addition of either irinotecan or methotrexate to bolus 5-fluorouracil and high-dose folinic acid every 2 weeks in advanced colorectal carcinoma: a randomised study by the Southern Italy Cooperative Oncology Group. [J] . Comella P, Crucitta E, De Vita F, Annals of oncology: official journal of the European Society for Medical Oncology . 2002,第6期

机译：在晚期结直肠癌中，每两周向大剂量5-氟尿嘧啶和大剂量亚叶酸中加用伊立替康或甲氨蝶呤：意大利南部合作肿瘤小组进行的一项随机研究。
4. FOLFOXIRI (folinic acid 5-fluorouracil oxaliplatin and irinotecan) vs FOLFIRI (folinic acid 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG) [O] . J Souglakos, N Androulakis, K Syrigos, 2006

机译：FOLFOXIRI（亚叶酸5-氟尿嘧啶奥沙利铂和伊立替康）与FOLFIRI（亚叶酸5-氟尿嘧啶和伊立替康）作为转移性结直肠癌（MCC）的一线治疗：来自希腊肿瘤研究组的多中心随机III期试验（霍格）
5. “Oxaliplatin plus high dose folinic acid and 5-fluoruracil i.v. bolus (OXAFAFU) versus irinotecan plus high dose folinic acid and 5-fluoruracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: Southern Italy Cooperative Oncology Group trial 0103” [O] . PASQUALE COMELLA, BRUNO MASSIDDA, GIANFRANCO FILIPPELLI, 2005

机译：“奥沙利铂加大剂量亚叶酸和5-氟尿嘧啶静脉注射静脉推注（OXAFAFU）与伊立替康加大剂量亚叶酸和5-氟尿嘧啶静脉注射转移性结直肠癌患者的大剂量推注（IRIFAFU）：意大利南部合作肿瘤小组试验0103”

Oxaliplatin plus high-dose folinic acid and 5-fluorouracil i.v. bolus (OXAFAFU) versus irinotecan plus high-dose folinic acid and 5-fluorouracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: a Southern Italy Cooperative Oncology Group phase III trial

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