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The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53

机译：双作用化疗药物Alchemix可以独立于ATM和p53诱导细胞死亡

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Yes

机译：是

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Thomas A.; Perry T.; Berhane S.; Oldreive C.; Zlatanou A.; Williams L.R.; Weston V.J.; Stankovic T.; Kearns P.; Pors Klaus; Grand R.J.; Stewart G.S.;
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1. AZD1775 induces toxicity through double-stranded DNA breaks independently of chemotherapeutic agents in p53-mutated colorectal cancer cells [J] . Webster Peter John, Littlejohns Anna Tiffany, Gaunt Hannah Jane, Cell cycle . 2017,第22期

机译：AZD1775通过双链DNA断裂诱导毒性，所述双链DNA在P53-突变结肠直肠癌细胞中独立于化学治疗剂
2. CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death [J] . J Wischhusen, U Naumann, H Ohgaki, Oncogene . 2003,第51期

机译：CP-31398，一种新型P53稳定剂，诱导P53依赖性和P53无闭合的胶质瘤细胞死亡
3. p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs [J] . RDG Malcomson, M Oren, AH Wyllie, British Journal of Cancer . 1995,第4期

机译：p53依赖性死亡和p53诱导的成纤维细胞凋亡预防作用
4. p53-Induced ROS-accumulation induces programmed cell death in C6 glioma cells [C] . Wang Gang, Wang JunJie, Li BaoYuan, International Conference on Information Science, Electronics and Electrical Engineering . 2014

机译：p53诱导的ROS积累在C6胶质瘤细胞中诱导程序性细胞死亡
5. Role of oncogenes in resistance of leukemic cells to apoptosis induced by conventional and novel chemotherapeutic agents. [D] . Decker, Roy Harold. 2001

机译：癌基因在白血病细胞对常规和新型化疗药物诱导的细胞凋亡的抗性中的作用。
6. AZD1775 induces toxicity through double-stranded DNA breaks independently of chemotherapeutic agents in p53-mutated colorectal cancer cells [O] . Peter John Webster, Anna Tiffany Littlejohns, Hannah Jane Gaunt, 2017

机译：AZD1775通过双链DNA断裂诱导毒性独立于p53突变的结直肠癌细胞中的化学治疗剂
7. AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells [O] . Webster, PJ, Littlejohns, AT, Gaunt, HJ, 2017

机译：aZD1775通过双链DNa诱导毒性，独立于p53突变的结肠直肠癌细胞中的化学治疗剂
8. Bifunctional Alkylating Agent-Induced p53 and Nonclassical Nuclear Factor kB Responses and Cell Death are Altered by Caffeic Acid Phenethyl Ester: A Potential Role for Antioxidant/Electrophilic Response-Element Signaling [R] . Minsavage, G. D. , Dillman, J. F. 2007

机译：双功能烷化剂诱导的p53和非经典核因子KB反应和细胞死亡由咖啡酸苯乙酯改变：抗氧化/亲电反应元素信号的潜在作用

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53

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