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Automatic image quality assessment and measurement of fetal head in two-dimensional ultrasound image

机译:二维超声图像中胎儿头部的自动图像质量评估和测量

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摘要

Owing to the inconsistent image quality existing in routine obstetric ultrasound (US) scans that leads to a large intraobserver and interobserver variability, the aim of this study is to develop a quality-assured, fully automated US fetal head measurement system. A texton-based fetal head segmentation is used as a prerequi- site step to obtain the head region. Textons are calculated using a filter bank designed specific for US fetal head structure. Both shape- and anatomic-based features calculated from the segmented head region are then fed into a random forest classifier to determine the quality of the image (e.g., whether the image is acquired from a correct imaging plane), from which fetal head measurements [biparietal diameter (BPD), occipital–frontal diam- eter (OFD), and head circumference (HC)] are derived. The experimental results show a good performance of our method for US quality assessment and fetal head measurements. The overall precision for automatic image quality assessment is 95.24% with 87.5% sensitivity and 100% specificity, while segmentation performance shows 99.27% (`0.26) of accuracy, 97.07% (`2.3) of sensitivity, 2.23 mm (`0.74) of the maximum symmetric contour distance, and 0.84 mm (`0.28) of the average symmetric contour distance. The statistical analysis results using paired t-test and Bland–Altman plots analysis indicate that the 95% limits of agreement for inter observer variability between the automated measurements and the senior expert measurements are 2.7 mm of BPD, 5.8 mm of OFD, and 10.4 mm of HC, whereas the mean differences are −0.038 ` 1.38 mm, −0.20 ` 2.98 mm, and −0.72 ` 5.36 mm, respectively. These narrow 95% limits of agreements indicate a good level of consistency between the automated and the senior expert’s measurements.
机译:由于常规产科超声(US)扫描中存在的图像质量不一致,导致观察者内部和观察者之间存在较大差异,因此本研究的目的是开发质量保证的,全自动的美国胎儿头部测量系统。基于Texton的胎儿头部分割被用作获取头部区域的必要步骤。使用为美国胎儿头部结构专门设计的过滤器组来计算Texton。然后,将从分割的头部区域计算出的基于形状和解剖结构的特征都输入到随机森林分类器中,以确定图像的质量(例如,是否从正确的成像平面获取图像),从中进行胎头测量[推导了双顶壁直径(BPD),枕额叶直径(OFD)和头围(HC)。实验结果表明我们的方法在美国质量评估和胎儿头部测量方面表现良好。自动图像质量评估的总体精度为95.24%,灵敏度为87.5%,特异度为100%,而分割性能显示精度为99.27%(`0.26),灵敏度为97.07%(`2.3),2.23 mm(`0.74)。最大对称轮廓距离,以及平均对称轮廓距离的0.84毫米(0.28)。使用配对t检验和Bland-Altman图分析的统计分析结果表明,自动测量与高级专家测量之间观察者间差异的一致性的95%限制为BPD 2.7 mm,OFD 5.8 mm和10.4 mm HC的平均值,而平均差分别为-0.038`1.38 mm,-0.20`2.98 mm和-0.72`5.36 mm。这些狭窄的95%协议限制表明,自动化和高级专家的测量之间具有良好的一致性。

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