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A bibliometric trend analysis of stem cells and regenerative medicine research output in Iran: comparison with the global research output

机译:伊朗干细胞和再生医学研究成果的文献计量趋势分析:与全球研究成果的比较

摘要

This report is a bibliometric analysis of the growth rates of publications in the fields of stem cells and tissue engineering and regenerative medicine in Iran and compares these rates with the rates in other regions of the world. PubMed database was used for extraction of relevant publications using MeSH terms. The data were extracted from 2001-2011 and the address fields of the publications were checked manually in order to allocate the publications to a relevant geographical region. Linear regression was used for fitting a linear model to the publications of a particular region and the slope of the model was used as an indicator of publication growth rate. Statistical comparison of the slopes of different regions showed that Iran enjoys a moderate growth rate in regards to tissue engineering and regenerative medicine publications (including stem cells-related papers) and a low growth rate in regards to general stem cells papers. Iran is a regionally dominant country in the field of tissue engineering but, not in the field of stem cells. Analysis of the annual growth rate showed a steady pattern of growth of tissue engineering papers and a random pattern of growth for general stem cells papers. This is an indication of instability in the general stem cell research and stability in the field of tissue engineering. Due to equal research funding opportunities, this observation is explained by the natural selection of the latter field by Iranian biomedical scientists. This natural selection should be supported and followed by policy makers in order to take advantage of current research interests and capabilities. It is recommended to view and manage stem cells research as a part of regenerative medicine not vice versa.
机译:该报告是对伊朗干细胞和组织工程与再生医学领域出版物增长率的文献计量分析,并将这些增长率与世界其他地区的增长率进行了比较。使用MeSH术语将PubMed数据库用于提取相关出版物。从2001-2011年提取数据,并手动检查出版物的地址字段,以将出版物分配到相关的地理区域。线性回归用于将线性模型拟合到特定区域的出版物,并且模型的斜率用作出版物增长率的指标。对不同地区斜率的统计比较表明,伊朗在组织工程学和再生医学出版物(包括与干细胞有关的论文)方面的增长率适中,而在一般干细胞论文方面的增长率较低。伊朗在组织工程领域是一个区域性主导国家,但在干细胞领域却不是。对年增长率的分析表明,组织工程论文的增长模式稳定,而普通干细胞论文的增长模式则随机。这表明一般干细胞研究的不稳定性和组织工程领域的稳定性。由于研究资金机会均等,伊朗生物医学科学家自然选择了后者,从而解释了这一现象。决策者应该支持并遵循这种自然选择,以便利用当前的研究兴趣和能力。建议将干细胞研究作为再生医学的一部分进行查看和管理,反之亦然。

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