In situ monitoring of mean blood oxygen saturation using extended modified lambert beer model

摘要

We present the use of Extended Modified Lambert-Beer model far optical monitoring of mean blood oxygensaturation (S,02) via a fitting praeedurc. This work facuses on the absorption characteristics of hemoglobin derivativesin the wavelength range of 520-600 nm to give the best estimate of SmO2. The study of the feasibility ofapplying this analytic method to skin oximetry is via spectroscopy data collected from fingertips of four healthyvolunteers both at rest and during arterial blood occlusion condition. The results revealed a decrease in the mean ofmean and standard deviation of S-r.O l. value of fingertips from 94.5 + 2.19% when volunteers were at rest to 56.76 &5.8% during the arterial blood occlusion measurement. The larger variation in the value estimated for blood occlusioncondition could be a result of differences in volunteers' physical fitness and hypertension status. These estimatedSm02 values agreed reasonably well with the value reported in most of the previous studies. This work concludedthat the purposed technique can potentially be used as a complementary technique to clinical assessment of skin grafts and burnt skin.