FPGA-in-the-loop co-simulation of reentrant arrhythmia mechanism in One Dimensional (1D) ring-shaped based on FitzHugh-Nagumo Model

摘要

This paper presents the simulation of reentrantexcitation-conduction of cardiac cells realized by coupling 80active circuits in one dimensional (1D) ring-shaped based onFitzHugh-Nagumo (FHN) model. 1D ring-shaped cable model isdesigned using Simulink in order to simulate an action potentialsignal and its conduction for a hardware design by using HDLCoder to automate the model for Very High Speed IntegratedCircuit (VHSIC) Hardware Description Language (VHDL) codegeneration. Then, the VHDL design is functionally verified on aField Programmable Gate Array (FPGA) Xilinx Virtex-6 boardusing HDL Verifier proving the model through FPGA-in-the-Loop (FIL) co-simulation approach. It can then be downloadedinto a target FPGA device for real-time simulations. This novelapproach of prototyping cardiac reentrant excitation-conductionprovides a fast and effective FPGA-based hardwareimplementation flow towards a stand-alone implementation toperform complex real-time simulations compared with manualHDL designs.