Prevalencia por infección por Helicobacter pylori y asociación con patalogías gástricas en pacientes adultos de chequeo ejecutivo desde enero del 2010 hasta septiembre del 2012 del Hospital Metropolitano de Quito-Ecuador.

摘要

INTRODUCTION: Helicobacter pylori infection has been described as highly prevalent worldwide, and its association with cytological changes that may progress to dysplasia and cancer is well established, this cross-sectional study was conducted with the intention of measuring the prevalence and association of premalignant infection in adult patients without symptoms of acute illness.OBJECTIVES: To determine the prevalence of Helicobacter pylori identified by biopsy and identify the potential relationship between the presence of infection with endoscopic and histopathological in this population.METHODS: Data were collected from 1147 patients during the months of November and December 2012 from the databases of the Endoscopy Unit and Pathology Department of the Hospital Metropolitano Quito- Ecuador, for the subjects who came to executive check from January 2010 through September 30, 2012. Once the information was determined, the prevalence of the infection and the association with endoscopic and histopathological findings were found.RESULTS: The prevalence of infection was 40.2% (95% CI: 37.4-43), was not associated with gender and found weakly associated with age. Infected individuals were younger (18 to 30 years) with 51.8%. 96% had some type of macroscopic alteration by EDA, while 80.5% showed histopathological alterations. Found in infected significantly: mild chronic gastritis (45.9%), ulcers (8.4%), glandular atrophy (30.6%), intestinal metaplasia (15%), grade II atypia (22.2%). Increasing age was associated with premalignant changes positively.CONCLUSION: This study showed that the prevalence of infection in apparently asymptomatic adult patients is high and younger age groups are more frequently infected. Likewise Helicobacter pylori is positively associated with inflammatory and premalignant lesions, this association being greater with age.