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Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO.

机译：设计的锚蛋白重复蛋白靶向NEMO的泛素结合/寡聚域，可抑制NF-κB活化。

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摘要

International audience

机译：国际观众

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作者
Wyler, Emanuel; Kaminska, Monika; Coïc, Yves-Marie; Baleux, Françoise; Véron, Michel; Agou, Fabrice;
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年度 2007
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正文语种 en
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1. Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO. [J] . Wyler E, Kaminska M, Coic YM, Protein Science: A Publication of the Protein Society . 2007,第9期

机译：设计的锚蛋白重复蛋白靶向NEMO的泛素结合/寡聚域，可抑制NF-κB活化。
2. Direct inhibition of NF-kappaB activation by peptide targeting the NOA ubiquitin binding domain of NEMO. [J] . Chiaravalli J, Fontan E, Fsihi H, Biochemical Pharmacology . 2011,第9期

机译：通过靶向NEMO的NOA泛素结合结构域的肽直接抑制NF-κB活化。
3. Structure-based Design of Pyridone–Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition [J] . Siegfried H. Reich, Paul A. Sprengeler, Gary G. Chiang, Journal of Medicinal Chemistry . 2018,第8期

机译：基于结构的吡啶胺 - 氨基EFT508靶向失调翻译通过选择性丝裂剂活化的蛋白激酶相互作用激酶1和2（MNK1 / 2）抑制作用
4. The Signal Pathways Of Immune Inflammation Mediated By The Tlr3/Nf-Kappab And Activator Protein-1 In Cells Infected With Influenza A Virus Antagonized By Baicalin [C] . Chunjing Zhang, Haitao Yu International Conference on Smart Materials and Nanotechnology in Engineering . 2012

机译：在感染甲虫拮抗的细胞中介导的TLR3 / NF-κB和活化剂蛋白-1介导的免疫炎症的信号途径
5. Roles of cellular FLICE-inhibitory protein (c-FLIP) and PI3K/Akt in Fas (CD95)-induced NF-kappaB activation and apoptosis through death effector domains. [D] . Lu, Bin. 2005

机译：细胞FLICE抑制蛋白（c-FLIP）和PI3K / Akt在Fas（CD95）诱导的NF-κB活化和细胞凋亡中通过死亡效应域的作用。
6. Inhibition of NF-κB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO [O] . Emanuel Wyler, Monika Kaminska, Yves-Marie Coïc, 2007

机译：设计针对NEMO的泛素结合/寡聚域的锚蛋白重复蛋白抑制NF-κB活化
7. Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO. [O] . Wyler, Emanuel, Kaminska, Monika, Coïc, Yves-Marie, 2007

机译：设计的锚蛋白重复蛋白靶向NEMO的泛素结合/寡聚域，可抑制NF-κB活化。

Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO.

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