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Histological evaluation of the effect of low-level laser on distraction osteogenesis in rabbit mandibles

机译:低强度激光对兔下颌骨牵张成骨作用影响的组织学评价

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摘要

OBJECTIVES: This study evaluated the action of low level laser therapy (LLLT) on the percentage of newly formed bone in rabbit mandibles that underwent distraction osteogenesis (DO). STUDY DESIGN: Ten rabbits underwent bone lengthening according to the following protocol: Latency - 3 days; Activation - 7 days 0.7 mm/d; and Consolidation - 10 days. The control group was composed of 4 rabbits. The experimental group, composed of 6 rabbits, received infrared GaAlAs LLLT (wavelength=830 nm, P=40 mW) according to the following protocol: point dose of 10 J/cm(2) applied directly on the bone site that underwent DO during bone consolidation at 48-hour intervals. RESULTS: The percentage of newly formed bone was greater in the LLLT group (57.89%) than in the control group (46.75%) (p=0.006). CONCLUSION: The results suggest that LLLT had a positive effect on the percentage of newly formed bone. Better-quality bone sites may allow early removal of the osteogenic distractors, thus shortening total treatment time.
机译:目的:本研究评估了低水平激光治疗(LLLT)对兔骨下颌骨新形成的骨百分比的影响,这些下颌骨经历了牵引成骨(DO)。研究设计:十只兔子按照以下方案进行骨延长:潜伏期-3天;激活-7天0.7毫米/天;和合并-10天。对照组由4只兔子组成。实验组由6只兔子组成,根据以下协议接受红外GaAlAs LLLT(波长= 830 nm,P = 40 mW):10 J / cm(2)的点剂量直接施用于在DO期间接受DO的骨部位每隔48小时进行一次骨固结。结果:LLLT组的新生骨百分比(57.89%)比对照组的更大(46.75%)(p = 0.006)。结论:结果表明LLLT对新形成的骨的百分比有积极的影响。更高质量的骨位点可允许及早去除成骨干扰物,从而缩短总治疗时间。

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