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The inhibition of Stat5 by a peptide aptamer ligand specific for the DNA binding domain prevents target gene transactivation and the growth of breast and prostate tumor cells

机译：对DNA结合结构域具有特异性的肽适体配体对Stat5的抑制作用可防止靶基因反式激活以及乳腺和前列腺肿瘤细胞的生长

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Weber Axel; Borghouts Corina; Brendel Christian; Moriggl Richard; Delis Natalia; Brill Boris; Vafaizadeh Vida; Groner Bernd;
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年度 2013
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1. The Inhibition of Stat5 by a Peptide Aptamer Ligand Specific for the DNA Binding Domain Prevents Target Gene Transactivation and the Growth of Breast and Prostate Tumor Cells [J] . Axel Weber, Bernd Groner, Boris Brill, Pharmaceuticals . 2013,第8期

机译：特定于DNA结合域的肽适体配体对Stat5的抑制作用可防止靶基因反式激活以及乳腺癌和前列腺肿瘤细胞的生长。
2. The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells. [J] . Nagel Wolfrum K, Buerger C, Wittig I, Molecular cancer research: MCR . 2004,第3期

机译：特定肽适体与转录因子Stat3的DNA结合结构域和二聚结构域的相互作用可抑制反式激活并诱导肿瘤细胞凋亡。
3. Peptide aptamers with binding specificity for the intracellular domain of the ErbB2 receptor interfere with AKT signaling and sensitize breast cancer cells to Taxol. [J] . Kunz C, Borghouts C, Buerger C, Molecular cancer research: MCR . 2006,第12期

机译：对ErbB2受体的细胞内结构域具有结合特异性的肽适体会干扰AKT信号传导并使乳腺癌细胞对紫杉醇敏感。
4. Development of Peptide Aptamers – 3d Complementary Ligands for Selective Binding of Target Biomarkers of Diseases in Multiparametric Sensor Systems [C] . Nikita O. Sitkov, Tatiana M. Zimina, Alexei V. Soloviev, IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering . 2019

机译：肽适体的发展 - 三维互补配体，用于多次传感器系统疾病靶生物标志物的选择性结合
5. Therapeutic Targeting of Stat5a/b in Advanced Prostate Cancer: Inhibition of Stat5a/b Suppresses Growth of Prostate Cancer through Mechanisms Dependent and Independent of Androgen Receptor. [D] . Hoang, David Timothy. 2016

机译：Stat5a / b在晚期前列腺癌中的治疗靶点：Stat5a / b的抑制作用通过依赖于雄激素受体的机制来抑制前列腺癌的生长。
6. The Inhibition of Stat5 by a Peptide Aptamer Ligand Specific for the DNA Binding Domain Prevents Target Gene Transactivation and the Growth of Breast and Prostate Tumor Cells [O] . Axel Weber, Corina Borghouts, Christian Brendel, 2013

机译：特定于DNA结合域的肽适体配体对Stat5的抑制作用可防止靶基因反式激活以及乳腺癌和前列腺肿瘤细胞的生长。
7. The Inhibition of Stat5 by a Peptide Aptamer Ligand Specific for the DNA Binding Domain Prevents Target Gene Transactivation and the Growth of Breast and Prostate Tumor Cells [O] . Vida Vafaizadeh, Bernd Groner, Boris Brill, 2013

机译：特异于DNa结合结构域的肽适体配体对stat5的抑制可防止靶基因反式激活和乳腺癌和前列腺肿瘤细胞的生长
8. Riboswitch-Mediated Aptamer Binding for Imaging and Therapy (RABIT): A Novel Technique to Selectively Target an Intracelluar Ligand Specific for Ovarian Cancer. [R] . Kolodny, G. M., Yisraeli, J. 2015

机译：用于成像和治疗的核糖开关介导的适体结合（RaBIT）：选择性靶向卵巢癌特异性细胞内配体的新技术。

The inhibition of Stat5 by a peptide aptamer ligand specific for the DNA binding domain prevents target gene transactivation and the growth of breast and prostate tumor cells

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