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Tertiary alkylamines as nucleophiles in substitution reactions at heteroaromatic halide during the synthesis of the highly potent pirinixic acid derivative 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS-121)

机译：叔烷基胺类化合物在合成强效吡rin酸衍生物2-（4-氯-6-（2,3-二甲基苯基氨基）嘧啶-2-基硫基）辛酸（YS-121）期间在杂芳族卤化物上的取代反应中成为亲核试剂

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Gabler Matthias; Schubert-Zsilavecz Manfred;
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年度 2011
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1. Tertiary Alkylamines as Nucleophiles in Substitution Reactions at Heteroaromatic Halide During the Synthesis of the Highly Potent Pirinixic Acid Derivative 2-(4-Chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic Acid (YS-121) [J] . Manfred Schubert-Zsilavecz, Matthias Gabler Molecules . 2011,第12期

机译：叔烷基胺类化合物作为高亲和力吡啶啉酸衍生物2-（4-氯-6-（2,3-二甲基苯基氨基）嘧啶-2-基硫基）辛酸（YS-121）在杂芳族卤化物上的取代反应中的亲核试剂
2. The molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. [J] . Koeberle A, Rossi A, Zettl The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2010,第3期

机译：2-（4-氯-6-（2,3-二甲基苯基氨基）嘧啶-2-基硫基）辛酸（YS121）（微粒体前列腺素E2合酶-1和5-脂氧合酶的双重抑制剂）的分子药理作用和体内活性。
3. Palladium-catalyzed cross-coupling reactions of pyridylboronic acids with heteroaryl halides bearing a primary amine group: Synthesis of highly substituted bipyridines and pyrazinopyridines [J] . Thompson AE, Hughes G, Batsanov AS, The Journal of Organic Chemistry . 2005,第1期

机译：吡啶基硼酸与带有伯胺基的杂芳基卤化物的钯催化交叉偶联反应：高度取代的联吡啶和吡嗪并吡啶的合成
4. α-Naphtyl Substituted Pirinixic Acid Derivatives as Potent Selective Agonists of the Peroxisome Proliferator-Activated Receptor Gamma [C] . Theresa M. Thieme, Ramona Steri, Ewgenij Proschak European Symposium on Organic Chemistry . 2009

机译：α-萘基取代的吡啶酸衍生物作为过氧化物体增殖物激活的受体γ的有效选择性激动剂
5. Molybdenum and palladium catalyzed asymmetric allylic alkylation of prochiral nucleophiles: Enantioselective synthesis of nonnatural alpha-amino acids and of tertiary alpha-hydroxy carboxylic acid derivatives. [D] . Franzini, Maurizio. 2005

机译：钼和钯催化的前手性亲核试剂的不对称烯丙基烷基化：非天然α-氨基酸和叔α-羟基羧酸衍生物的对映选择性合成。
6. Tertiary Alkylamines as Nucleophiles in Substitution Reactions at Heteroaromatic Halide During the Synthesis of the Highly Potent Pirinixic Acid Derivative 2-(4-Chloro-6-(23-dimethylphenylamino)pyrimidin-2-ylthio)octanoic Acid (YS-121) [O] . Matthias Gabler, Manfred Schubert-Zsilavecz 2011

机译：叔烷基胺作为亲核试剂在高强的吡喃酸衍生物2-（4-氯-6-（23-二甲基苯基氨基）嘧啶-2-基硫基）辛酸（YS-121）合成过程中在杂芳族卤化物上的取代反应中的亲核体
7. Tertiary Alkylamines as Nucleophiles in Substitution Reactions at Heteroaromatic Halide During the Synthesis of the Highly Potent Pirinixic Acid Derivative 2-(4-Chloro-6-(2,3dimethylphenylamino)pyrimidin-2-ylthio)octanoic Acid (YS-121) [O] . Matthias Gabler, Manfred Schubert-zsilavecz 2013

机译：叔烷基胺作为亲核试剂在高强环丙氨酸衍生物2-（4-氯-6-（2,3-二甲基苯基氨基）嘧啶-2-基硫基）辛酸（YS-121）合成过程中在杂芳族卤化物上的取代反应中

Tertiary alkylamines as nucleophiles in substitution reactions at heteroaromatic halide during the synthesis of the highly potent pirinixic acid derivative 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS-121)

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