Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux

摘要

13 páginas, 9 figuras. This research was originally published in Journal of Biological Chemistry. Franco M.L., Melero C., Sarasola E., Acebo P., Luque A., Calatayud-Baselga I., Garcia-Barcina M.,Vilar M. (2016). Mutations in TrkA causing congenital insensitivity to pain with anhidrosis (CIPA) induce misfolding, aggregation and mutation-dependent neurodegeneration by dysfunction of the autophagic flux. J Biol Chem 291(41): 21363-74. © the American Society for Biochemistry and Molecular Biology.