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Chitin whiskers reinforced carrageenan films as low adhesion cell substrates

机译:几丁质晶须增强了角叉菜胶薄膜作为低粘附力细胞的基质

摘要

Carrageenan was used to prepare carrageenan films reinforced with chitin nanowhiskers. Atomic force microscopy was used to characterize the morphology and roughness of the films. Structural characterization was performed using X-ray diffraction and Fourier transform infrared spectroscopy. The mechanical properties were assessed by tensile tests. The prepared nanocomposites were used as cell substrate in order to explore their potential biological applications. HeLa cells were seeded on the samples in order to assess their biocompatibility. The preliminary results show good cell proliferation but low cell adhesion, demonstrating a potential application of this novel material as substrate for tumor cell culture.
机译:角叉菜胶用于制备用几丁质纳米晶须增强的角叉菜胶薄膜。原子力显微镜用于表征薄膜的形貌和粗糙度。使用X射线衍射和傅里叶变换红外光谱进行结构表征。通过拉伸试验评估机械性能。制备的纳米复合材料被用作细胞基质,以探索其潜在的生物学应用。将HeLa细胞接种在样品上,以评估其生物相容性。初步结果显示出良好的细胞增殖能力,但细胞粘附力低,证明了这种新型材料作为肿瘤细胞培养基质的潜在应用。

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