We report on the evaluation of rare earth (Er3þ, Eu3þ, and Tb3þ ions) SiO2 sub-micrometricspheres as potential optically controllable temperature sensors. Details about fabrication, opticalmanipulation and spectroscopic characterization of the sub-micrometric spheres are presented.The fluorescence properties of the micros-spheres in the biological range (25–60 C) have beensystematically investigated. From this systematic study, the thermal resolution potentiallyachieved in each case has been determined and compared to previous works.
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