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Therapeutic Effectiveness of Nutrition Therapy in Pediatric Patientsudwith Chronic Liver Diseases Awaiting Liver Transplantation

机译:营养疗法对小儿患者的治疗效果 ud肝移植的慢性肝病患者

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摘要

AbstractudIt is important to prevent protein/calorie malnutrition in children with end stage liver diseases prior toudtransplantation. This study involved 34 patients between the ages of 10 and 156 months (mean value 25.69udmonths  32.2) (13 females and 21 males) on the liver transplant waiting list. Data collected as of three monthsudbefore transplant and up to ten months after the procedure concerned gender, age, weight, height, Pediatric EndudStage Liver Disease Score, baseline pathology, type of nutrition, type of transplant, immunosuppression, pulseudsteroid therapy, length of stay, and post transplant complications. Linear regression analysis showed that theudlength of hospital stay was 24.5 days more for females than for males, but also that intensive nutrition therapyudshortens this stay for both female patients (P = 0.085) and younger patients (P = 0.023). The study populationudwas divided into two groups according to the different nutritional therapies adopted. The Student’s t-test andudMann-Whitney test evidenced that the group receiving intensive nutrition therapy grew taller compared with theudgroup following an oral diet (mean -1.37 and Prob = 0.043); that females grew taller compared to males (meanud-1.65 +/- 0.56); and that there was an increase in height among the children in the group receiving intensiveudnutrition therapy despite the presence (-1.37 +/- 0.56) or absence (-14.8 +/- 5.44 and Prob = 0.035) ofudcomplications, and despite the administration (-1.03 +/- 0.33) or non administration (-1.48 +/- 0.55 and Prob =ud0.019) of steroids. Intensive nutrition therapy enhances the velocity of growth in height and shortens the lengthudof hospital stay, thus optimizing the final prognosis of the baseline pathology.
机译:摘要 ud在移植结束前预防晚期肝病患儿的蛋白质/热量营养不良很重要。这项研究纳入了10到156个月大的34例患者(平均价值25.69 udmonths32.2)(13例女性和21例男性)。截至移植前三个月手术后至十个月为止收集的数据涉及性别,年龄,体重,身高,小儿末期肝病评分,基线病理学,营养类型,移植类型,免疫抑制,脉搏类固醇治疗,住院时间和移植后并发症。线性回归分析表明,女性的住院时间比男性多了24.5天,而且强化营养疗法也缩短了女性患者(P = 0.085)和年轻患者(P = 0.023)的住院时间。根据所采用的不同营养疗法,将研究人群分为两组。学生的t检验和udMann-Whitney检验证明,与接受口服饮食的ud组相比,接受强化营养治疗的组长得更高(平均-1.37,Prob = 0.043);女性比男性长高(平均 ud-1.65 +/- 0.56);尽管存在( -1.37 +/- 0.56)或不存在(-14.8 +/- 5.44和Prob = 0.035)不存在并发症,并且接受了强化营养治疗的儿童中身高有所增加给予类固醇(-1.03 +/- 0.33)或不给予(-1.48 +/- 0.55和Prob = ud0.019)。强化营养疗法可提高身高增长速度,缩短住院时间,从而优化基线病理的最终预后。

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