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Barium study associated with water siphon test in gastroesophageal reflux disease and its complications.

机译:与水虹吸试验有关的食管反流性疾病及其并发症的钡剂研究。

摘要

PURPOSE:udThe aim of this study was to evaluate the role of digital cineradiography associated with the water siphon test (WST) in the diagnosis of gastroesophageal reflux and to compare the results with oesophageal motility study, pH monitoring and endoscopy associated with biopsy and histology.udMATERIALS AND METHODS:udOne hundred and sixty consecutive patients underwent digital cineradiography with WST, motility study, pH monitoring and endoscopy with biopsy. The presence of gastroesophageal reflux, oesophagitis, Barrett''s oesophagus and intestinal metaplasia was evaluated.udRESULTS:udWST vs. pH monitoring showed sensitivity of 71%, specificity of 31%, positive predictive value (PPV) of 53% and negative predictive value (NPV) of 50%; when middle-proximal refluxes only were considered, sensitivity decreased to 45% and specificity increased to 55%. Furthermore, the association between reflux and oesophagitis demonstrated by the chi-square (chi(2)) test proved to be statistically significant both for WST and pH monitoring, whereas the association between reflux and Barrett''s oesophagus was not significant for either WST or for pH monitoring. With regard to intestinal metaplasia, WST (middle-proximal refluxes) showed higher sensitivity (64% vs. 58%) and specificity (63% vs. 51%) than pH monitoring, whereas the statistical association between reflux and metaplasia proved to be significant for WST but not for pH monitoring.udCONCLUSIONS:udWST is a simple, inexpensive and reliable test that might be useful in the diagnosis of gastroesophageal reflux disease (GERD). A positive WST might be an additional indication for endoscopy with biopsy.
机译:目的: ud本研究的目的是评估与数字虹吸照相术相关的水虹吸试验(WST)在胃食管反流的诊断中的作用,并将结果与​​食管蠕动研究,pH监测以及与活检和组织学相关的内窥镜检查进行比较 ud材料与方法: ud连续对160例患者进行了WST数字电影摄影,运动研究,pH监测和内窥镜活检。评估了胃食管反流,食道炎,巴雷特食管和肠上皮化生的情况。 udRESULTS: udWST与pH监测显示敏感性为71%,特异性为31%,阳性预测值(PPV)为53%,阴性预测值(NPV)为50%;仅考虑中近端反流时,敏感性降低至45%,特异性提高至55%。此外,卡方检验(chi(2))证明反流与食管炎之间的关联在WST和pH监测中均具有统计学意义,而反流与Barrett食道之间的关联对于任一WST均不显着或用于pH监测。关于肠上皮化生,WST(中近端反流)显示出比pH监测更高的敏感性(64%vs. 58%)和特异性(63%vs. 51%),而反流与化生之间的统计学联系被证明是显着的 ud结论: udWST是一种简单,廉价且可靠的测试,可能对诊断胃食管反流病(GERD)有用。 WST阳性可能是活检内窥镜检查的另一指征。

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