Synthesis, characterization, chiral separa tion and carbon-carbon double bonds reduction of chalcone using phenylsulfonyl hydrazide

摘要

Recent study on chalcone derivatives has attracted much attention due to itsudgreat interest in pharmacological activities such as potential cytotoxic agents,udantimicrobial agents, 'antiviral, anti flammatory, anesthetic, and etc. There areudvarious methods used to synthesize' chalcone. The most common used isudClaisen-Schmidt condensation of aldehyde and ketone by base catalysed orudacid catalysed. The reactions of substituted chalcones with phenyl sulfonyludhydrazide in ethanol resulted in the reduction of the carbon-carbon doubleudbond of the chalcones.