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The design and simulation of a planar microarray dot electrode for a dielectrophoretic lab-on-chip device

机译:介电泳芯片实验室设备的平面微阵列点电极的设计与仿真

摘要

Dielectrophoresis (DEP) has been proven as a method of manipulating and analyzing the electrophysiological properties of bioparticles by applying non-uniform electric fields generated through special electrodes. Various electrode geometries have been developed to address different applications. Electric field simulation over electrodes is essential in order to optimize the generated DEP force for cell manipulation. This paper describes the study of electric field distribution over planar multiple microarray dot electrodes using numerical modeling of Comsol Multiphysics 4.2a®. Electric field evaluation for different dot sizes has been demonstrated by applying a range of frequencies to the designed electrodes. Results show that the electric field is axisymmetrical around the center of the dot aperture and that it is higher at the dot edges than the dot centers. Furthermore, adding ground plane between adjacent dots increases the electric field strength. © 2012 by ESG.
机译:介电电泳(DEP)已被证明是通过施加通过特殊电极产生的非均匀电场来操纵和分析生物粒子的电生理特性的方法。已经开发出各种电极几何形状以解决不同的应用。电极上的电场模拟对于优化产生的细胞操作DEP力至关重要。本文介绍了使用Comsol Multiphysics4.2a®的数值模型研究平面多个微阵列点电极上的电场分布的研究。通过对设计的电极施加一定范围的频率,已证明了对不同点尺寸的电场评估。结果表明,电场在点孔中心周围呈轴对称,并且在点边缘处的电场高于点中心。此外,在相邻点之间添加接地平面会增加电场强度。 ©2012,ESG。

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