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Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas

机译：第2阶段随机，灵活的交叉，双盲，沙呢基转移酶抑制剂的抑制剂刺激剂抑制剂，在儿童和年轻成人中，具有神经纤维瘤病的1型和渐进式的丛状神经纤维腈

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B. C. Widemann; E. Dombi; A. Gillespie; P. L. Wolters; J. Belasco; S. Goldman; B. R. Korf; J. Solomon; S. Martin; W. Salzer; E. Fox; N. Patronas; M. W. Kieran; J. P. Perentesis; A. Reddy; J. J. Wright; A. Kim; S. M. Steinberg; F. M. Balis;
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1. Phase 2 randomized, flexible crossover, double-blinded,placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas [J] . Brigitte C. Widemann, Eva Dombi, Andrea Gillespie, Neuro-Oncology . 2014,第5期

机译：法尼基转移酶抑制剂替非法尼在患有1型神经纤维瘤和进行性丛状神经纤维瘤的儿童和青少年中的2期随机，灵活，交叉，双盲，安慰剂对照试验
2. Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas. [J] . Widemann BC, Salzer WL, Arceci RJ, Journal of Clinical Oncology . 2006,第3期

机译：法尼基转移酶抑制剂替非法尼在难治性实体瘤或I型神经纤维瘤病和丛状神经纤维瘤儿童的I期试验和药代动力学研究。
3. Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas [J] . WidemannB.C., Babovic-VuksanovicD., DombiE., Pediatric blood & cancer . 2014,第9期

机译：吡非尼酮在患有1型神经纤维瘤病和进行性丛状神经纤维瘤的儿童和青少年中的II期试验
4. Phase 2 randomized flexible crossover double-blinded placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas [O] . Brigitte C. Widemann, Eva Dombi, Andrea Gillespie, 2014

机译：法尼基转移酶抑制剂替非法尼在患有1型神经纤维瘤病和进行性丛状神经纤维瘤的儿童和年轻人中的2期随机灵活交叉双盲安慰剂对照试验
5. Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study [O] . B. Weiss, B. C. Widemann, P. Wolters, 2014

机译：渐进式神经纤维瘤症的西罗司......相关七斑神经纤维瘤：神经纤维瘤术临床试验联盟II期研究
6. Prospective Randomized Clinical Trial of Celecoxib for the Control of Symptomatic Plexiform Neurofibroma in Neurofibromatosis 1 [R] . Gusella, J. F. , Plotkin, S. 2005

机译：塞来昔布用于控制神经纤维瘤病中症状性丛状神经纤维瘤的前瞻性随机临床试验1

Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas

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