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Design, Synthesis and Biological Evaluation of 4-Aryl-5,7-dihydro-6H-pyrrolo2,3-dpyrimidin-6-one Derivatives as a PI3Kα Inhibitor

机译：4-芳基-5,7-二氢-6的设计，合成和生物学评价-6 -Pyrrolo 2,3- D 嘧啶-6-一种衍生物作为a PI3Kα抑制因素

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Shengquan Hu; Zhichang Zhao; Yeming Ni; Hongxing Xin; Hong Yan; Xiuqing Song;
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1. Design, Synthesis and Biological Evaluation of 4-Aryl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one Derivatives as a PI3K alpha Inhibitor [J] . Hu Shengquan, Zhao Zhichang, Ni Yeming, Biological & pharmaceutical bulletin . 2019,第6期

机译：4-芳基-5,7-二氢-6H-Pyrrolo [2,3-D]嘧啶-6-一种衍生物作为PI3Kα抑制剂的设计，合成和生物学评价
2. Design, Synthesis and Biological Evaluation of 4-Aryl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one Derivatives as a PI3K alpha Inhibitor [J] . Hu Shengquan, Zhao Zhichang, Ni Yeming, Biological & pharmaceutical bulletin . 2019,第6期

机译：4-芳基-5,7-二氢-6H-Pyrrolo [2,3-D]嘧啶-6-一种衍生物作为PI3Kα抑制剂的设计，合成和生物学评价
3. Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors [J] . Yu Yanan, Han Yuqiao, Zhang Fupo, Journal of Medicinal Chemistry . 2020,第6期

机译：咪唑[1,2-A]吡啶衍生物作为新型PI3K / mTOR双抑制剂的设计，合成和生物学评价
4. Indentification of Pharmacophore Model, Synthesis and biological evaluation of N-phenyl-1-arylamide and N-phenylbenzenesulfonamide derivatives as BACE 1 inhibitors [C] . Wenhai Huang, Haiping Yu, Rong Sheng, 第四届国际分子模拟与信息技术应用学术会议（The 4th International Conference of Molecular Simulations and Applied Informatics Technologies）论文集 . 2008

机译：N-苯基-1-芳酰胺和N-苯基苯磺酰胺衍生物作为BACE 1抑制剂的药理模型鉴定，合成及生物学评价
5. Structure-Based Drug Design in Medicinal Chemistry: I. Development of Translesion Synthesis Inhibitors II. Synthesis and Biological Evaluation of Sulfonyl Piperazine Derivatives for LpxH Inhibition [D] . Lee, Minhee 2017

机译：药物化学中基于结构的药物设计：I.跨病变合成抑制剂的开发II。磺酰哌嗪衍生物对LpxH的抑制作用及其合成及生物学评价
6. Design Synthesis and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors [O] . Lide Yu, Qinqin Wang, Caolin Wang, 2019

机译：新型噻吩并嘧啶衍生物作为PI3Kα抑制剂的设计合成和生物学评价
7. Novel 4-Acrylamido-Quinoline Derivatives as Potent PI3K/mTOR Dual Inhibitors: The Design, Synthesis, and in vitro and in vivo Biological Evaluation [O] . Xiaodong Ma, Li Shen, Jiankang Zhang, 2019

机译：新型4-丙烯酰胺 - 喹啉衍生物作为有效的PI3K / MTOR双抑制剂：设计，合成和体外和体内生物评估

Design, Synthesis and Biological Evaluation of 4-Aryl-5,7-dihydro-6H-pyrrolo2,3-dpyrimidin-6-one Derivatives as a PI3Kα Inhibitor

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