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Design, synthesis and biological evaluation of novel 2-phenyl pyrimidine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors

机译：新型2-苯基嘧啶衍生物的设计，合成和生物学评价为有效的Bruton的酪氨酸激酶（BTK）抑制剂

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Xinyu Li; Binyu Shi; Yu Teng; Yu Cheng; Huizhu Yang; Jiurong Li; Lianjian Wang; Siying He; Qidong You; Hua Xiang;
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2. Design, synthesis and biological evaluation of novel 2-phenyl pyrimidine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors [J] . Xinyu Li, Binyu Shi, Yu Teng, MedChemComm . 2019,第2期

机译：新型2-苯基嘧啶衍生物的设计，合成和生物学评价为有效的Bruton的酪氨酸激酶（BTK）抑制剂
3. Design, synthesis and biological evaluation of novel 3-substituted pyrazolopyrimidine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors [J] . Zheng Nan, Pan Jing, Hao Qun, Bioorganic and medicinal chemistry . 2018,第8期

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4. Design, synthesis and evaluation of novel 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as potent, selective and reversible Bruton's tyrosine kinase (BTK) inhibitors for the treatment of rheumatoid arthritis [J] . Zhang Chufeng, Pei Heying, He Jun, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2019,第期

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5. Taking Quinazoline as a General Support-Nog to Design Potent and Selective Kinase Inhibitors: Application to FMS-like Tyrosine Kinase 3 [C] . Wei-Wei Li, Luo-Ding Yu, Li-Juan Chen, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

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7. Design synthesis and biological evaluation of novel 2-phenyl pyrimidine derivatives as potent Brutons tyrosine kinase (BTK) inhibitors [O] . Xinyu Li, Binyu Shi, Yu Teng, 2019

机译：新型2-苯基嘧啶衍生物作为有效的布鲁顿酪氨酸激酶（BTK）抑制剂的设计合成和生物学评估
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机译：Bruton Tyrosine激酶（BTK）抑制剂Acalabrutinib在两种小鼠慢性淋巴细胞白血病模型中显示出有效的靶向效果和功效

Design, synthesis and biological evaluation of novel 2-phenyl pyrimidine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors

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