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Population pharmacokinetics and exposure–response modeling and simulation for evolocumab in healthy volunteers and patients with hypercholesterolemia

机译：健康志愿者和高胆固醇血症患者Evolocumab的人口药代动力学和曝光响应建模和仿真

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Mita Kuchimanchi; Anita Grover; Maurice G. Emery; Ransi Somaratne; Scott M. Wasserman; John P. Gibbs; Sameer Doshi;
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1. Population pharmacokinetics and exposure–response modeling and simulation for evolocumab in healthy volunteers and patients with hypercholesterolemia [J] . Mita Kuchimanchi, Anita Grover, Maurice G. Emery, Journal of pharmacokinetics and pharmacodynamics . 2018,第3期

机译：健康志愿者和高胆固醇血症患者Evolocumab的人口药代动力学和曝光响应建模和仿真
2. Population pharmacokinetic-pharmacodynamic modeling of TF-505 using extension of indirect response model by incorporating a circadian rhythm in healthy volunteers. [J] . Matsumoto Y, Fujita T, Ishida Y, Biological & pharmaceutical bulletin . 2005,第8期

机译：通过纳入健康志愿者的昼夜节律，使用间接响应模型的扩展对TF-505进行群体药代动力学研究。
3. Population pharmacokinetics and safety of eptifibatide in healthy Chinese volunteers and simulations on the dose regimens approved for a Western population [J] . Wang Xi-pei, Zhou Zhi-ling, Yang Min, International journal of clinical pharmacology and therapeutics . 2015,第8期

机译：依替非巴肽在健康中国志愿者中的药代动力学和安全性以及对西方人群批准的剂量方案的模拟
4. Cardiovascular response to sinusoidal neck suction in healthy volunteers and orthostatic intolerance patients [C] . Widesott, L., Bernardi, . 2002

机译：健康志愿者和体位不耐受患者对正弦颈吸引的心血管反应
5. Clinical pharmacokinetic simulation/modeling as a tool for therapeutic drug monitoring and dose adjustment in special patient populations. [D] . Mohamed, Osama H. 2004

机译：临床药代动力学模拟/建模，作为特殊患者人群中治疗药物监测和剂量调整的工具。
6. Population pharmacokinetics and exposure–response modeling and simulation for evolocumab in healthy volunteers and patients with hypercholesterolemia [O] . Mita Kuchimanchi, Anita Grover, Maurice G. Emery, -1

机译：健康志愿者和高胆固醇血症患者的依维洛单抗的群体药代动力学和暴露-响应模型与模拟
7. 1536. Population Pharmacokinetic Analysis of Baloxavir Morboxil, a Cap-Dependent Endonuclease Inhibitor, in Adult and Adolescent Healthy Subjects and Influenza Patients and Exposure-Response Relationships in the Patients at High-Risk of Influenza Complications [O] . Hiroki Koshimichi, Sylvie Retout, Valérie F Cosson, 2019

机译：1536.鲍罗唑莫尔克尔（Baloxavir Morboxil）的人口药代动力学分析，含有青少年健康受试者和流感患者的患者中依赖性内切核酸酶抑制剂和患者的暴露 - 反应关系，高危流感并发症

Population pharmacokinetics and exposure–response modeling and simulation for evolocumab in healthy volunteers and patients with hypercholesterolemia

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