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Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide, a Repurposed Drug with Poor Bioavailability

机译：肝胃和肠道代谢对尼卡洛酰胺的配置，一种具有差的生物利用度差的重新灌注的药物

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Xiaoyu Fan; Hongmin Li; Xinxin Ding; Qing-Yu Zhang;
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1. Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide, a Repurposed Drug with Poor Bioavailability [J] . Fan Xiaoyu, Li Hongmin, Ding Xinxin, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2019,第7期

机译：肝胃和肠道代谢对尼卡洛酰胺的配置，一种具有差的生物利用度差的重新培育药物
2. Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin [J] . Toxicology and Applied Pharmacology . 2012,第3期

机译：UDP-葡糖醛酸糖基转移酶与多药耐药相关蛋白的结合是造成大黄素肠道分布和生物利用度差的原因
3. Mechanisms Responsible for Poor Oral Bioavailability of Paeoniflorin: Role of Intestinal Disposition and Interactions with Sinomenine [J] . Zhong Qiu Liu, Zhi Hong Jiang, Liang Liu, Pharmaceutical Research . 2006,第12期

机译：eon药苷口服生物利用度低下的机制：肠道处置的作用和与青藤碱的相互作用
4. Agent-Based Simulation of In Vitro Hepatic Drug Metabolism: In Silico Hepatic Intrinsic Clearance [C] . Shahab Sheikh-Bahaei, Glen E. P. Ropella, C. Anthony Hunt Spring Simulation Multiconference and Business and Industry Symposium(BIS'05);Agent-Directed Simulation Symposium; 20050403-07;20050403-07; San Diego,CA(US);San Diego,CA(US) . 2005

机译：基于Agent的体外肝药物代谢模拟：硅胶肝内在清除率
5. Application of pharmacokinetic theory to examine roles of transporters and enzymes in intestinal and hepatic drug disposition. [D] . Sun, Huadong. 2008

机译：应用药代动力学理论研究转运蛋白和酶在肠道和肝脏药物处置中的作用。
6. Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide a Repurposed Drug with Poor Bioavailability [O] . Xiaoyu Fan, Hongmin Li, Xinxin Ding, -1

机译：肝脏和肠道代谢对生物利用度较差的改用药物Niclosamide处置的贡献
7. Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of 14CCobimetinib, a MEK Inhibitor, in Humans [O] . R. H. Takahashi, E. F. Choo, S. Ma, 2015

机译：吸收，代谢，排泄和肠道代谢对14C Cobimetinib，兆蛋白，人类的口腔抑制剂的贡献

Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide, a Repurposed Drug with Poor Bioavailability

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